2-bromo-4-chloro-1,3-thiazole
2-Bromo-4-chlorothiazole
CAS: 139670-03-4
Molecular Formula: C3HBrClNS
2-bromo-4-chloro-1,3-thiazole - Names and Identifiers
| Name | 2-Bromo-4-chlorothiazole |
| Synonyms | 2-Bromo-4-chlorothiazole Thiazole, 2-bromo-4-chloro- 2-bromo-4-chloro-1,3-thiazole |
| CAS | 139670-03-4 |
| EINECS | 604-604-1 |
2-bromo-4-chloro-1,3-thiazole - Physico-chemical Properties
| Molecular Formula | C3HBrClNS |
| Molar Mass | 198.47 |
| Density | 1.979±0.06 g/cm3(Predicted) |
| Boling Point | 216.7±13.0 °C(Predicted) |
| pKa | -1.93±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-bromo-4-chloro-1,3-thiazole - Introduction
2-Bromo-4-chroothiazole (2-Bromo-4-chroothiazole) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White to light yellow crystalline powder.
-Solubility: Soluble in ethanol, dimethylformamide and ether, slightly soluble in water.
-Melting point: about 54-56 ℃.
Use:
-2-Bromo-4-chroothiazole is a versatile organic compound commonly used in the synthesis of drugs and pesticides.
-It can also be used as a dye intermediate and other starting materials for organic synthesis.
-In organic synthesis, it is often used as a reagent to replace or add functional groups.
Preparation Method:
- 2-Bromo-4-chlorothiazole can be prepared by reacting 2-amino-4-thiothiazole with bromine and chloride.
-First, 2-amino-4-thiothiazole is reacted with bromine to generate 2-bromo-4-thiothiazole.
-Then, under alkaline conditions, 2-bromo-4-thiothiazole is reacted with sodium chloride to replace the bromine on the sulfur atom with chlorine to generate 2-Bromo-4-chlorothiazole.
Safety Information:
-2-Bromo-4-chroothiazole has certain toxicity to the human body and may affect the central nervous system and respiratory system.
-Wear appropriate protective equipment to avoid contact with skin, eyes and respiratory tract.
-materials should be stored in a cool, dry place, and away from flammable substances and oxidizing agents.
-Be careful to follow the relevant safety procedures during handling and storage, and be equipped with appropriate safety equipment.
Nature:
-Appearance: White to light yellow crystalline powder.
-Solubility: Soluble in ethanol, dimethylformamide and ether, slightly soluble in water.
-Melting point: about 54-56 ℃.
Use:
-2-Bromo-4-chroothiazole is a versatile organic compound commonly used in the synthesis of drugs and pesticides.
-It can also be used as a dye intermediate and other starting materials for organic synthesis.
-In organic synthesis, it is often used as a reagent to replace or add functional groups.
Preparation Method:
- 2-Bromo-4-chlorothiazole can be prepared by reacting 2-amino-4-thiothiazole with bromine and chloride.
-First, 2-amino-4-thiothiazole is reacted with bromine to generate 2-bromo-4-thiothiazole.
-Then, under alkaline conditions, 2-bromo-4-thiothiazole is reacted with sodium chloride to replace the bromine on the sulfur atom with chlorine to generate 2-Bromo-4-chlorothiazole.
Safety Information:
-2-Bromo-4-chroothiazole has certain toxicity to the human body and may affect the central nervous system and respiratory system.
-Wear appropriate protective equipment to avoid contact with skin, eyes and respiratory tract.
-materials should be stored in a cool, dry place, and away from flammable substances and oxidizing agents.
-Be careful to follow the relevant safety procedures during handling and storage, and be equipped with appropriate safety equipment.
Last Update：2024-04-09 21:01:54
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CAS: 139670-03-4
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