2-chloro-3-fluoro-pyridine-4-carbaldehyde
2-chloro-3-fluoro-pyridine-4-carbaldehyde
CAS: 329794-28-7
Molecular Formula: C6H3ClFNO
2-chloro-3-fluoro-pyridine-4-carbaldehyde - Names and Identifiers
2-chloro-3-fluoro-pyridine-4-carbaldehyde - Physico-chemical Properties
| Molecular Formula | C6H3ClFNO |
| Molar Mass | 159.55 |
| Density | 1.424 g/mL at 25 °C |
| Boling Point | 231.7±35.0 °C(Predicted) |
| Flash Point | 108℃ |
| Vapor Presure | 6.75E-05mmHg at 25°C |
| pKa | -1.42±0.10(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | n20/D1.543 |
| MDL | MFCD04972388 |
2-chloro-3-fluoro-pyridine-4-carbaldehyde - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
2-chloro-3-fluoro-pyridine-4-carbaldehyde - Introduction
Is an organic compound whose chemical formula is C6H3ClFNO. The following is an introduction to its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid.
-Solubility: It is soluble in many organic solvents, such as chloroform, dimethyl sulfoxide and dichloromethane.
-Melting point: Its melting point range is between -25 and -20 degrees Celsius.
-Boiling point: Its boiling point range is between 103 and 104 degrees Celsius.
-Stability: relatively stable at room temperature, but may decompose when heated and exposed to sunlight.
Use:
-It is often used as an organic synthetic intermediate for the synthesis of drugs, pesticides, dyes and other compounds.
-It can also be used as a raw material for fungicides and preservatives.
Method:
Generally, the preparation of phosphonium can be carried out through the following steps:
1. In an appropriate solvent, pyridine is reacted with ferrous chloride to obtain chloropyridine.
2. Reaction of chloropyridine with trifluoroethyl alcohol to give 3-chloro-2-fluoropyridine.
3. React 3-chloro-2-fluoropyridine with formaldehyde to obtain pyridine.
Safety Information:
-is an organic compound that should be handled with care and follow laboratory safety procedures.
-It may irritate the eyes, respiratory system and skin, so you should pay attention to protective measures when using it.
-When handling or storing this compound, maintain proper ventilation and avoid inhaling its vapors.
-If taken by mistake or in the eyes or skin, rinse immediately with plenty of water and seek medical advice.
Please note that this information is for reference only. The specific operation should follow the relevant safety operation guidelines and conduct the experiment in a safe environment.
Nature:
-Appearance: Colorless to light yellow liquid.
-Solubility: It is soluble in many organic solvents, such as chloroform, dimethyl sulfoxide and dichloromethane.
-Melting point: Its melting point range is between -25 and -20 degrees Celsius.
-Boiling point: Its boiling point range is between 103 and 104 degrees Celsius.
-Stability: relatively stable at room temperature, but may decompose when heated and exposed to sunlight.
Use:
-It is often used as an organic synthetic intermediate for the synthesis of drugs, pesticides, dyes and other compounds.
-It can also be used as a raw material for fungicides and preservatives.
Method:
Generally, the preparation of phosphonium can be carried out through the following steps:
1. In an appropriate solvent, pyridine is reacted with ferrous chloride to obtain chloropyridine.
2. Reaction of chloropyridine with trifluoroethyl alcohol to give 3-chloro-2-fluoropyridine.
3. React 3-chloro-2-fluoropyridine with formaldehyde to obtain pyridine.
Safety Information:
-is an organic compound that should be handled with care and follow laboratory safety procedures.
-It may irritate the eyes, respiratory system and skin, so you should pay attention to protective measures when using it.
-When handling or storing this compound, maintain proper ventilation and avoid inhaling its vapors.
-If taken by mistake or in the eyes or skin, rinse immediately with plenty of water and seek medical advice.
Please note that this information is for reference only. The specific operation should follow the relevant safety operation guidelines and conduct the experiment in a safe environment.
Last Update：2024-04-09 20:49:11
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