2-chloro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-Chloropyridine-4-boronic acid pinacol ester
CAS: 458532-84-8
Molecular Formula: C11H15BClNO2
2-chloro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine - Names and Identifiers
2-chloro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine - Physico-chemical Properties
| Molecular Formula | C11H15BClNO2 |
| Molar Mass | 239.51 |
| Density | 1.14±0.1 g/cm3(Predicted) |
| Melting Point | 64.7-64.8°C |
| Boling Point | 338.2±27.0 °C(Predicted) |
| Flash Point | 158.3°C |
| Vapor Presure | 0.000196mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Light yellow to Light orange |
| pKa | -0.58±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.505 |
| MDL | MFCD04039870 |
2-chloro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| Hazard Class | IRRITANT |
2-chloro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine - Introduction
2-Chloropyridine-4-boronic acid pinacol ester is an organic compound with the chemical formula C12H15BClNO2. It is a white solid, relatively stable at room temperature. The following is an introduction to the nature, use, preparation and safety information of 2-Chloropyridine-4-boronic acid pinacol ester:
Nature:
-Appearance: White solid
-Molecular weight: 254.52g/mol
-Melting point: about 75-80°C
-Solubility: 2-Chloropyridine-4-boronic acid pinacol ester is soluble in organic solvents such as chloroform, methanol and dichloromethane.
Use:
- 2-Chloropyridine-4-boronic acid pinacol ester is an important intermediate in organic synthesis, which is used to synthesize various organic compounds containing boron functional groups.
-It is one of the ligands in metal-catalyzed reactions and is widely used in C- C bond formation reactions, carbonylation reactions, cross-coupling reactions and functional reactions of aromatic hydrocarbons.
Preparation Method:
The preparation method of 2-Chloropyridine-4-boronic acid pinacol ester can be achieved by the reaction of pyridine-4-boronic acid and 2-chloropyridine. The specific synthesis process needs to be carried out under an inert atmosphere.
Safety Information:
2-Chloropyridine-4-boronic acid pinacol ester generally has no obvious harm to human body and environment when used and handled correctly. However, as an organic compound, it may have irritating effects on the eyes, skin and respiratory system. Take proper precautions during handling and storage to avoid contact with skin or inhalation of vapors. In case of accidental contact, rinse immediately with water and seek medical help. During use, please make sure to work in a well-ventilated place and operate in accordance with appropriate laboratory practices.
Nature:
-Appearance: White solid
-Molecular weight: 254.52g/mol
-Melting point: about 75-80°C
-Solubility: 2-Chloropyridine-4-boronic acid pinacol ester is soluble in organic solvents such as chloroform, methanol and dichloromethane.
Use:
- 2-Chloropyridine-4-boronic acid pinacol ester is an important intermediate in organic synthesis, which is used to synthesize various organic compounds containing boron functional groups.
-It is one of the ligands in metal-catalyzed reactions and is widely used in C- C bond formation reactions, carbonylation reactions, cross-coupling reactions and functional reactions of aromatic hydrocarbons.
Preparation Method:
The preparation method of 2-Chloropyridine-4-boronic acid pinacol ester can be achieved by the reaction of pyridine-4-boronic acid and 2-chloropyridine. The specific synthesis process needs to be carried out under an inert atmosphere.
Safety Information:
2-Chloropyridine-4-boronic acid pinacol ester generally has no obvious harm to human body and environment when used and handled correctly. However, as an organic compound, it may have irritating effects on the eyes, skin and respiratory system. Take proper precautions during handling and storage to avoid contact with skin or inhalation of vapors. In case of accidental contact, rinse immediately with water and seek medical help. During use, please make sure to work in a well-ventilated place and operate in accordance with appropriate laboratory practices.
Last Update：2024-04-10 22:29:15
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Product Name: 2-Chloropyridine-4-boronic acid pinacol ester Visit Supplier Webpage Request for quotation
CAS: 458532-84-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 458532-84-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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