2-chloro-4-(trifluoromethyl)phenylhydrazine - Names and Identifiers
2-chloro-4-(trifluoromethyl)phenylhydrazine - Physico-chemical Properties
Molecular Formula | C7H6ClF3N2
|
Molar Mass | 210.58 |
Density | 1.487±0.06 g/cm3(Predicted) |
Melting Point | 39 °C |
Boling Point | 80-85°C 0,25mm |
pKa | 3.89±0.27(Predicted) |
Storage Condition | 2-8℃ |
2-chloro-4-(trifluoromethyl)phenylhydrazine - Risk and Safety
Hazard Symbols | Xi - Irritant

|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S23 - Do not breathe vapour.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Class | IRRITANT |
2-chloro-4-(trifluoromethyl)phenylhydrazine - Introduction
2-chloro-4-(trifluoromethyl)phenylhydrazine is an organic compound with the chemical formula C7H5ClF3N2.
Nature:
-Appearance: White solid
-Melting point: 69-73 ℃
-Boiling point: unstable, will decompose
-Solubility: Insoluble in water, soluble in organic solvents such as methanol, ethanol and ether solvents.
Use:
2-chloro-4-(trifluoromethyl)phenylhydrazine is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used in the synthesis of phenylhydrazine derivatives and other organic compounds, such as pesticides, dyes and pharmaceuticals.
Preparation Method:
2-chloro-4-(trifluoromethyl)phenylhydrazine can be obtained by reacting phenylhydrazine with trifluoromethyl chloride in the following steps:
1. Under appropriate reaction conditions, phenylhydrazine is reacted with trifluoromethyl chloride in an alkaline solvent, such as sodium hydroxide solution.
2. After the reaction has been carried out for a period of time, the product is separated from the reaction mixture by heating or washing.
3. The product was crystallized or further purified to obtain the final 2-chloro-4-(trifluoromethyl)phenylhydrazine.
Safety Information:
2-choro-4-(trifluoromethyl)phenylhydrazine is generally safe under normal operating conditions, but the following matters still need to be noted:
-Avoid inhalation, contact with skin and eyes.
-Use appropriate personal protective equipment such as lab gloves, safety glasses and protective clothing during use.
-Avoid swallowing or inhaling dust during operation.
-Keep away from fire and heat sources during storage and handling, and maintain a well-ventilated environment.
-In case of accidental contact or ingestion, immediately flush the affected area with plenty of water and seek medical help.
Last Update:2024-04-09 19:05:52