2-chloro-4-pyridinol
2-chloro-4-pyridinol
CAS: 17368-12-6
Molecular Formula: C5H4ClNO
2-chloro-4-pyridinol - Names and Identifiers
| Name | 2-chloro-4-pyridinol |
| Synonyms | 2-CHLORO-4-PYRIDINOL 2-chloro-4-pyridinol 2-CHLOROPYRIDIN-4-OL 2-chloro-1H-pyridin-4-one 2-chloro-4-hydroxypyridine 2-CHLORO-4-HYDROXYPYRIDINE 4-Pyridinol,2-chloro-(7CI,8CI,9CI) 2-Chloro-4-hydroxypyridine HCl Salt 2-Chloro-4-hydroxypyridine hydrochloride |
| CAS | 17368-12-6 |
| EINECS | 241-399-3 |
| InChI | InChI=1/C5H4ClNO/c6-5-3-4(8)1-2-7-5/h1-3H,(H,7,8) |
| InChIKey | VBEHFOMFHUQAOW-UHFFFAOYSA-N |
2-chloro-4-pyridinol - Physico-chemical Properties
| Molecular Formula | C5H4ClNO |
| Molar Mass | 129.54 |
| Density | 1.392±0.06 g/cm3(Predicted) |
| Melting Point | 169-172°C |
| Boling Point | 401.8±25.0 °C(Predicted) |
| Solubility | soluble in Methanol |
| Appearance | yellowish-like powder |
| Color | White to Light yellow to Light orange |
| pKa | 7.94±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| MDL | MFCD01646108 |
| Physical and Chemical Properties | Light yellow powder |
2-chloro-4-pyridinol - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
2-chloro-4-pyridinol - Introduction
2-choro-4-pyridinol, chemical formula C5H4ClNO, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
2-choro-4-pyridinol is a white to light yellow crystal with a special nitrogen heterocyclic structure. It has a certain solubility and can be dissolved in water and organic solvents. It decomposes at high temperatures and is unstable.
Use:
2-choro-4-pyridinol is commonly used as catalyst, complexing agent and additive in organic synthesis. It can promote the reaction rate and selectivity in chemical catalytic reactions, and is widely used in organic synthesis, drug synthesis and materials science.
Method:
There are many preparation methods of 2-chloro-4-pyridinol. One commonly used method is to react 2-chloro-4-aminopyridine with alcohol in the presence of alkali, the product was purified by distillation. During the preparation process, attention should be paid to the control of operating temperature and reaction conditions.
Safety Information:
2-chloro-4-pyridinol has certain toxicity and may cause irritation and damage to the human body. Wear appropriate personal protective equipment such as safety glasses, protective gloves and protective clothing during use or operation. At the same time, avoid contact with skin, eyes and respiratory tract, so as not to cause discomfort or injury. When used in applications, follow relevant safety practices and appropriate waste disposal measures.
Nature:
2-choro-4-pyridinol is a white to light yellow crystal with a special nitrogen heterocyclic structure. It has a certain solubility and can be dissolved in water and organic solvents. It decomposes at high temperatures and is unstable.
Use:
2-choro-4-pyridinol is commonly used as catalyst, complexing agent and additive in organic synthesis. It can promote the reaction rate and selectivity in chemical catalytic reactions, and is widely used in organic synthesis, drug synthesis and materials science.
Method:
There are many preparation methods of 2-chloro-4-pyridinol. One commonly used method is to react 2-chloro-4-aminopyridine with alcohol in the presence of alkali, the product was purified by distillation. During the preparation process, attention should be paid to the control of operating temperature and reaction conditions.
Safety Information:
2-chloro-4-pyridinol has certain toxicity and may cause irritation and damage to the human body. Wear appropriate personal protective equipment such as safety glasses, protective gloves and protective clothing during use or operation. At the same time, avoid contact with skin, eyes and respiratory tract, so as not to cause discomfort or injury. When used in applications, follow relevant safety practices and appropriate waste disposal measures.
Last Update：2024-04-09 21:11:58
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