2-chloro-5-(phenylmethoxy)-pyrimidine

2-chloro-5-(phenylmethoxy)-pyrimidine - Names and Identifiers

Name	2-Chloro-5-(phenylmethoxy)-pyrimidine
Synonyms	5-(benzyloxy)-2-chloropyrimidine 2-chloro-5-(phenylmethoxy)-pyrimidine 2-Chloro-5-(phenylmethoxy)-pyrimidine Pyrimidine, 2-chloro-5-(phenylmethoxy)- Benzenesulfonylchloride,9-(acetylamino)- 5-(benzyloxy)-2-chloropyrimidine138274-14-3 1,3-Dioxane-4,6-dione,2,2-dimethyl-7-phenyl-
CAS	138274-14-3
InChI	InChI=1/C11H9ClN2O/c12-11-13-6-10(7-14-11)15-8-9-4-2-1-3-5-9/h1-7H,8H2

2-chloro-5-(phenylmethoxy)-pyrimidine - Physico-chemical Properties

Molecular Formula	C11H9ClN2O
Molar Mass	220.65
Density	1.278±0.06 g/cm3(Predicted)
Melting Point	187.9℃
Boling Point	387.0±17.0 °C(Predicted)
pKa	-1.28±0.22(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.593
MDL	MFCD09744017

2-chloro-5-(phenylmethoxy)-pyrimidine - Introduction

2-Chloro-5-(benzyloxy) pyrimidine is an organic compound with the chemical formula C12H10ClN3O. It is a white crystalline solid with low solubility.

The following are some of the properties and uses of 2-chloro-5-(benzyloxy) pyrimidine:
-Properties: 2-chloro-5-(benzyloxy) pyrimidine is a heterocyclic aromatic compound with certain stability. It is soluble in some organic solvents such as dimethyl sulfoxide and chloroform, and hardly soluble in water.

-Purpose: 2-Chloro-5-(benzyloxy) pyrimidine is often used as a pharmaceutical intermediate in medicinal chemistry. It can be used to synthesize some biologically active compounds, such as antiviral drugs and anticancer drugs.

-preparation method: 2-chloro-5-(benzyloxy) pyrimidine can be prepared by reacting 2-amino-5-(benzyloxy) pyrimidine with thionyl chloride or phosphorus pentachloride, and then appropriately treating to obtain the target product.

-Safety information: Since 2-chloro-5-(benzyloxy) pyrimidine is a chemical substance, you should pay attention to safety when using it. It is irritating and may cause irritation to the eyes, skin, and respiratory tract, make sure to wear appropriate personal protective equipment when handling. In addition, if necessary, should be used in a well-ventilated place, and avoid contact with food, drinking water and combustible materials. When using and storing, please follow the recommendations provided in the safety data sheet.

Last Update：2024-04-09 21:04:16