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2-chloro-5-(trifluoromethyl)-pyridin

2-Chloro-5-(trifluoromethyl)pyridine

CAS: 52334-81-3

Molecular Formula: C6H3ClF3N

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2-chloro-5-(trifluoromethyl)-pyridin - Names and Identifiers

Name 2-Chloro-5-(trifluoromethyl)pyridine
Synonyms 5-CTF
2,5-CTF
oro-5-(trifL
2 - chloro - 5-3 Methyl pyridine
2-Chloro-5-trifluoromethylpyridine
2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE
2-Chloro-5-(trifluoromethyl)pyridine
2-chloro-5-(trifluoromethyl)-pyridin
2-choro-5-(trifluoromethyl) pyridine
2-chloro-5-(trifluoromethyl) pyridine
2-chlorine-5-trifluoromethyl pyridine
CAS 52334-81-3
EINECS 257-856-5
InChI InChI=1/C6H3ClF3N/c7-5-2-1-4(3-11-5)6(8,9)10/h1-3H
InChIKey JFZJMSDDOOAOIV-UHFFFAOYSA-N

2-chloro-5-(trifluoromethyl)-pyridin - Physico-chemical Properties

Molecular FormulaC6H3ClF3N
Molar Mass181.54
Density1.417g/mLat 25°C(lit.)
Melting Point32-34°C(lit.)
Boling Point152 °C
Flash Point>230°F
AppearanceCrystalline Low Melting Solid
Specific Gravity1.417
ColorWhite to yellow
BRN3649688
pKa-2.57±0.10(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
MDLMFCD00042225
Physical and Chemical PropertiesDensity 1.417
melting point 29-33°C
boiling point 152°C
flash point 65°C
UseUsed as a pesticide intermediate

2-chloro-5-(trifluoromethyl)-pyridin - Risk and Safety

Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R25 - Toxic if swallowed
R11 - Highly Flammable
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S22 - Do not breathe dust.
S16 - Keep away from sources of ignition.
UN IDs2811
WGK Germany3
RTECSUS7530000
TSCAT
HS Code29339900
Hazard NoteIrritant
Hazard Class6.1
Packing GroupIII

2-chloro-5-(trifluoromethyl)-pyridin - Reference Information

EPA chemical information Information provided by: ofmpub.epa.gov (external link)
Use 2-chloro-5-trifluoromethylpyridine is an intermediate of the herbicides pyrifluoxaline and flupirchloroxaline, It is also an intermediate of the insecticide fluazinourea.
The intermediate of the herbicide pyrifluoxazole. At present, fluorine-containing pesticide intermediates are in urgent need of vigorous development. In addition to this product, 2-hydroxy-3-chloro-trifluoromethylphenol, p-chlorotrifluorotoluene, 3 ',3'-trifluoro-2'-chloropropene, 3-phenoxy-4-fluorobenzaldehyde are important varieties.
Used as pesticide intermediate
pesticide intermediate; pharmaceutical intermediate; liquid crystal material intermediate
Production method It is obtained by fluorination of 2-chloro-5-trichloromethylpyridine.
The preparation method is based on 3-methylpyridine as the raw material, first chlorinated to obtain 2-chloro-5-trichloromethylpyridine, and then further fluorinated to obtain the product; also can use 3-methylpyridine As a raw material, the product is obtained by performing a chlorofluorination reaction in the presence of a catalyst. You can also use 2-chloro-5-methylpyridine as a raw material, use chlorine to first chlorinate the side chain to 2-chloro-5-trichloromethylpyridine, and then use hydrogen fluoride to obtain the product. See the reaction formula:
Last Update：2024-04-09 21:11:58
2-chloro-5-(trifluoromethyl)-pyridin
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Tel: +86-17551318830
Email: r@reformchem.com­
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Product Name: 2-Chloro-5-(trifluoromethyl)pyridine Request for quotation
CAS: 52334-81-3
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
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Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 2-Chloro-5-(trifluoromethyl)pyridine Request for quotation
CAS: 52334-81-3
Tel: 0086-551-65418684
Email: sales@tnjchem.com
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Tel: 86+027-83389957
Email: 1024042217@qq.com
Mobile: 86+18627766980
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 2-Chloro-5-(trifluoromethyl)pyridine Visit Supplier Webpage Request for quotation
CAS: 52334-81-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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Shanghai Worldyang Chemical Co.,Ltd.
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Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
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Wechat: 13651600618
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CAS: 52334-81-3
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