2-chloro-5-fluoronicotinaMide
2-chloro-5-fluoronicotinaMide
CAS: 75302-64-6
Molecular Formula: C6H4ClFN2O
2-chloro-5-fluoronicotinaMide - Names and Identifiers
| Name | 2-chloro-5-fluoronicotinaMide |
| Synonyms | 2-chloro-5-fluoronicotinaMide 2-chloro-5-fluoro-pyridine-3-carboxamide 3-Pyridinecarboxamide, 2-chloro-5-fluoro- |
| CAS | 75302-64-6 |
2-chloro-5-fluoronicotinaMide - Physico-chemical Properties
| Molecular Formula | C6H4ClFN2O |
| Molar Mass | 174.56 |
| Density | 1.485±0.06 g/cm3(Predicted) |
| Melting Point | 137-139 °C |
| Boling Point | 247.6±40.0 °C(Predicted) |
| pKa | 13.65±0.50(Predicted) |
| Storage Condition | 2-8°C |
2-chloro-5-fluoronicotinaMide - Upstream Downstream Industry
| Downstream Products | 2-Chloro-5-fluoronicotinonitrile |
2-chloro-5-fluoronicotinaMide - Introduction
Is an organic compound with the chemical formula C6H3ClFNO. The following is a description of some properties, uses, preparation and safety information about this compound:
Nature:
-Appearance: White solid.
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and methanol.
-Melting point: Its melting point is about 140-142 degrees Celsius.
-Density: The density is about 1.47g/cm³.
Use:
-Pharmaceutical field: Commonly used in the synthesis of a variety of drugs and drug intermediates. For example, it can be used as a synthetic raw material for camphor tablets, anti-tumor drugs and anti-tuberculosis drugs.
Method:
A common preparation method is a step-by-step synthesis starting with 2-chloro-5-fluorocyanobenzene. 2-Chloro-5-fluorocyanobenzene is first converted to 2-chloro-5-fluorobenzonitrile by the action of hydrochloric acid or acid. 2-Chloro-5-fluorobenzonitrile was then converted to fluorobenzonitrile by the action of aqueous ammonia.
Safety Information:
-is an organic compound that needs to be handled with care. During operation, laboratory safety regulations should be followed and appropriate personal protective equipment such as gloves and goggles should be worn.
-It may be irritating to the skin, eyes and respiratory tract, so avoid skin contact and inhalation of gases, vapors, mist or dust.
-If contact occurs, flush the affected area immediately with plenty of water and seek medical attention.
Nature:
-Appearance: White solid.
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and methanol.
-Melting point: Its melting point is about 140-142 degrees Celsius.
-Density: The density is about 1.47g/cm³.
Use:
-Pharmaceutical field: Commonly used in the synthesis of a variety of drugs and drug intermediates. For example, it can be used as a synthetic raw material for camphor tablets, anti-tumor drugs and anti-tuberculosis drugs.
Method:
A common preparation method is a step-by-step synthesis starting with 2-chloro-5-fluorocyanobenzene. 2-Chloro-5-fluorocyanobenzene is first converted to 2-chloro-5-fluorobenzonitrile by the action of hydrochloric acid or acid. 2-Chloro-5-fluorobenzonitrile was then converted to fluorobenzonitrile by the action of aqueous ammonia.
Safety Information:
-is an organic compound that needs to be handled with care. During operation, laboratory safety regulations should be followed and appropriate personal protective equipment such as gloves and goggles should be worn.
-It may be irritating to the skin, eyes and respiratory tract, so avoid skin contact and inhalation of gases, vapors, mist or dust.
-If contact occurs, flush the affected area immediately with plenty of water and seek medical attention.
Last Update：2024-04-09 20:49:11
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Product Name: Nicotinamide Impurity 130 Visit Supplier Webpage Request for quotationCAS: 75302-64-6
Tel: 0714-3999186
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Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 2-chloro-5-fluoronicotinaMide Visit Supplier Webpage Request for quotation
CAS: 75302-64-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 75302-64-6
Tel: 18301782025
Email: 3008007409@qq.com
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Downstream Products for 2-chloro-5-fluoronicotinaMide