2-chloro-6-(trifluoromethyl)Pyrazine

2-chloro-6-(trifluoromethyl)Pyrazine - Names and Identifiers

Name	2-chloro-6-(trifluoromethyl)Pyrazine
Synonyms	2-chloro-6-(trifluoromethyl)Pyrazine 2-Chloro-6-(trifluoroMethyl)pyrazine 2-chloro-6-(trifluoromethyl)-Pyrazine Pyrazine, 2-chloro-6-(trifluoromethyl)- 2-Chloro-6-(trifluoromethyl)-1,4-diazine
CAS	61655-69-4

2-chloro-6-(trifluoromethyl)Pyrazine - Physico-chemical Properties

Molecular Formula	C5H2ClF3N2
Molar Mass	182.53
Density	1.504±0.06 g/cm3(Predicted)
Boling Point	141.2±35.0 °C(Predicted)
pKa	-3.13±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-chloro-6-(trifluoromethyl)Pyrazine - Introduction

2-chloro-6-(trifluoromethyl)Pyrazine is an organic compound with the chemical formula C5H2ClF3N2. It is a colorless crystalline solid, stable at room temperature. The following is an introduction to some of the properties and uses of this compound:

Nature:
-Appearance: Colorless crystalline solid
-Molecular weight: 190.53g/mol
-Melting Point: 78-81°C
-Boiling Point: 223-224°C
-Density: 1.62g/cm³
-Solubility: insoluble in water, soluble in organic solvents such as ethanol, dimethylformamide, etc.

Use:
2-chloro-6-(trifluoromethyl)Pyrazine is an important organic synthesis intermediate, which is commonly used in the synthesis of drugs, pesticides and dyes. It is commonly used in the field of medicine to synthesize antibacterial drugs, anticancer drugs and other bioactive molecules. In the field of pesticides, it can be used to prepare insecticides and fungicides. In addition, it can also be used in the preparation of dyes and electronic materials.

Preparation Method:
2-chloro-6-(trifluoromethyl)Pyrazine can be prepared by reacting pyrazine with trifluoromethylcupric chloride. The pyrazine is first reacted with trifluoromethylcupric chloride, then the product is treated with sodium hydroxide, and finally the product is formed by the action of an acid.

Safety Information:
Under reasonable use and storage conditions, 2-chloro-6-(trifluoromethyl)Pyrazine generally have low toxicity. However, it is still a chemical and needs to be handled properly. It is necessary to follow proper laboratory safety procedures during operation, such as wearing personal protective equipment (e. g. gloves, goggles, etc.). It should be stored in a sealed container, away from fire and oxidizing agents. If ingestion or exposure to the skin or eyes, seek medical advice immediately.

Last Update：2024-04-09 20:52:54