2-chloro-6-methylbenzenamine
2-Chloro-6-methylaniline
CAS: 87-63-8
Molecular Formula: C7H8ClN
2-chloro-6-methylbenzenamine - Names and Identifiers
| Name | 2-Chloro-6-methylaniline |
| Synonyms | 6-chloro-o-toluidine o-Toluidine, 6-chloro- 2-Amino-3-chlorotoluene 2-CHLORO-6-METHYLANINILE 2-Chloro-6-Methylaninile 2-Chloro-6-methylaniline 2-methyl-6-chloro aniline 2-chloro-6-methylbenzenamine 2-Chloro-6-methyl-phenylamine benzenamine,2-chloro-6-methyl- BENZENEAMINE,2-CHLORO-6-METHYL- benzenamine,2-chloro-6-methyl-(6-cot) |
| CAS | 87-63-8 |
| EINECS | 201-759-2 |
| InChI | InChI=1/C7H8ClN/c1-5-3-2-4-6(8)7(5)9/h2-4H,9H2,1H3 |
| InChIKey | WFNLHDJJZSJARK-UHFFFAOYSA-N |
2-chloro-6-methylbenzenamine - Physico-chemical Properties
| Molecular Formula | C7H8ClN |
| Molar Mass | 141.6 |
| Density | 1.152g/mLat 25°C(lit.) |
| Melting Point | 10-12°C(lit.) |
| Boling Point | 215°C(lit.) |
| Flash Point | 210°F |
| Water Solubility | Immiscible |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| Vapor Presure | 0.151mmHg at 25°C |
| Appearance | Oil |
| Color | Clear Colourless to Pale Purple |
| BRN | 774624 |
| pKa | 2.51±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.576(lit.) |
| Physical and Chemical Properties | Clear wine-red liquid. |
| Use | Used as pharmaceutical, pesticide, dye intermediates |
2-chloro-6-methylbenzenamine - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN 3429 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | XU5100000 |
| TSCA | Yes |
| HS Code | 29214300 |
| Hazard Class | 6.1 |
| Packing Group | III |
2-chloro-6-methylbenzenamine - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | 2-chloro-6-methylaniline is an important pharmaceutical intermediate for the synthesis of dasatinib. Dasatinib is an oral tyrosine kinase inhibitor developed by Bristol-Myers Squibb. The drug was approved by the FDA in June 2006 for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. |
| Use | for pharmaceutical, pesticide, dye intermediate |
Last Update：2024-04-09 21:01:54
Supplier List
Product Name: 2-Chloro-6-methylaniline Request for quotation
CAS: 87-63-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 87-63-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: 2-Chloro-6-methylaniline Request for quotation
CAS: 87-63-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 87-63-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
View History