2-cyano-N-(4-fluorobenzyl)acetamide - Names and Identifiers
2-cyano-N-(4-fluorobenzyl)acetamide - Physico-chemical Properties
Molecular Formula | C10H9FN2O
|
Molar Mass | 192.19 |
Density | 1.210±0.06 g/cm3(Predicted) |
Boling Point | 430.4±35.0 °C(Predicted) |
pKa | 5.36±0.10(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD01355686 |
2-cyano-N-(4-fluorobenzyl)acetamide - Risk and Safety
2-cyano-N-(4-fluorobenzyl)acetamide - Introduction
2-Cyano-N-(4-fluorobenzyl) acetamide is a compound with the formula C11H10FN3O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow crystalline solid.
-Melting point: about 106-107 degrees Celsius.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide.
-Structure: This compound contains a nitrile group (CN) and a fluorobenzyl group (C6H4CH2F).
Use:
- 2-Cyano-N-(4-fluorobenzyl) acetamide can be used as a pharmaceutical intermediate for the synthesis of other compounds.
-It can also be used as a reaction reagent in organic synthesis.
Preparation Method:
The preparation method of-2-Cyano-N-(4-fluorobenzyl) acetamide can be obtained by reacting nicotinic acid methylene with 4-fluorobenzylamine under alkaline conditions. In the course of the reaction, Mr. into the intermediate of the amide, followed by reaction with cyanamide to obtain the target product.
Safety Information:
-Since 2-Cyano-N-(4-fluorobenzyl) acetamide is a compound for chemical synthesis, it is necessary to comply with the safe practice of chemical experiments.
-Wear appropriate personal protective equipment, such as lab gloves and safety glasses, when handling the compound.
-Waste that requires proper preservation and disposal of the compound.
-Avoid contact with oxidants and strong acids during use, storage and transportation.
Last Update:2024-04-09 21:04:16