2-ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane - Names and Identifiers

Name	Ethylboronic acid pinacol ester
Synonyms	Ethylboronic acid pinacol ester 2-Ethylboronic acid, pinacol ester 2-Ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 2-ethyl-4,4,5,5-tetramethyl- 1,3,2-Dioxaborolane, 2-ethyl-4,4,5,5-tetraMethyl- (4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethane
CAS	82954-89-0

2-ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane - Physico-chemical Properties

Molecular Formula	C8H17BO2
Molar Mass	156.03
Density	0.87±0.1 g/cm3(Predicted)
Boling Point	79-81℃ / 120mbar
Appearance	clear liquid
Color	Colorless to Almost colorless
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.4090-1.4130

2-ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane - Risk and Safety

UN IDs	3272
Hazard Class	3
Packing Group	III

2-ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane - Introduction

Ethylboronic acid pinacol ester is an organic compound with the chemical formula C12H20BO2. It is the product of the esterification of ethyl boronic acid and pinacol.

Ethylboronic acid pinacol ester is stable and soluble in organic solvents such as chloroform, methanol and ether. It is a colorless or light yellow liquid, is not volatile at room temperature. It has a lower melting and boiling point.

Ethylboronic acid pinacol ester has important applications in organic synthesis. It can be used as a catalyst and reagent to participate in chemical reactions such as boronation, reduction and carbon-carbon bond coupling reactions. It can catalyze a series of reactions, such as Suzuki coupling reaction, Heck coupling reaction and Sonogashira coupling reaction. It can also be used as an intermediate in the preparation of other compounds.

the preparation method of Ethylboronic acid pinacol ester is generally obtained by esterification reaction of ethyl boric acid and pinacol under acid catalysis. The reaction is usually carried out at room temperature or under heating, and purification and extraction may be carried out after the reaction.

Regarding the safety information of Ethylboronic acid pinacol ester, it is irritating to skin and eyes, so it is necessary to wear appropriate protective equipment, such as gloves and goggles, when handling. At the same time, it should be kept away from fire and hot spots and stored in a well-ventilated place. During use and handling, care should be taken to avoid inhaling its vapor or contact with skin and eyes. In case of discomfort caused by misuse, aspiration or accidental contact, seek medical attention in time.

Last Update：2024-04-10 22:29:15