2-fluoro-1H-1,3-benzodiazole
1H-Benzimidazole, 2-fluoro-
CAS: 57160-78-8
Molecular Formula: C7H5FN2
2-fluoro-1H-1,3-benzodiazole - Names and Identifiers
| Name | 1H-Benzimidazole, 2-fluoro- |
| Synonyms | 2-Fluorobenzimidazole 2-Fluoro-1H-benzimidazole 1H-Benzimidazole, 2-fluoro- 2-fluoro-1H-1,3-benzodiazole 2-Fluoro-1H-benzo[d]imidazole 1H-Benzimidazole,2-fluoro-(9CI) |
| CAS | 57160-78-8 |
| InChI | InChI=1/C7H5FN2/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H,9,10) |
2-fluoro-1H-1,3-benzodiazole - Physico-chemical Properties
| Molecular Formula | C7H5FN2 |
| Molar Mass | 136.13 |
| Density | 1.370±0.06 g/cm3(Predicted) |
| Boling Point | 302.7±25.0 °C(Predicted) |
| Flash Point | 136.9°C |
| Vapor Presure | 0.000975mmHg at 25°C |
| pKa | 9.55±0.10(Predicted) |
| Refractive Index | 1.658 |
2-fluoro-1H-1,3-benzodiazole - Introduction
1H-Benzimidazole, 2-fluoro-is an organic compound whose chemical structure contains a benzimidazole ring and a fluorine atom is substituted on the benzene ring. The following is a description of some properties, uses, methods and safety information about 1H-Benzimidazole, 2-fluoro:
Nature:
-Appearance: 1H-Benzimidazole, 2-fluoro-is white to yellow crystal or crystal powder.
-Solubility: Its solubility in water is relatively low, but it can be dissolved in some organic solvents, such as ethanol, methanol and dichloromethane.
-Melting point: The melting point of 1H-Benzimidazole, 2-fluoro-is about 180-182 degrees Celsius.
Use:
-Pharmaceutical field: 1H-Benzimidazole, 2-fluoro-is an important intermediate compound that can be used to synthesize a variety of drugs and bioactive molecules. It has potential applications in the treatment of pathogenic microbial infections and the development of anti-cancer drugs.
-Pesticide field: The compound can also be used to prepare pesticides to protect plants from pathogens and insects.
Preparation Method:
The preparation method of 1H-Benzimidazole, 2-fluoro-can be obtained by reacting benzimidazole and fluorinated hydrocarbon. Specific steps are as follows:
1. The benzimidazole is dissolved in an appropriate organic solvent.
2. Add a fluorinated hydrocarbon, such as 2-fluoroethyl acetate or fluorobenzene.
3. Reaction at appropriate temperature and time conditions.
4. The product was obtained by filtration, and after proper treatment and purification, 1H-Benzimidazole, 2-fluoro-was obtained-.
Safety Information:
- 1H-Benzimidazole, 2-fluoro-is generally stable under normal conditions, but appropriate protective measures are still needed to avoid contact or inhalation.
-Wear appropriate protective gloves and eye protection when handling the compound to avoid skin contact and inhalation of gases, fumes or dust.
-It should be stored in a sealed container, away from fire and oxidizing agents, and avoid exposure to direct sunlight.
-Follow proper laboratory procedures and safety guidelines during handling and use.
Please note that the above information is for reference only. In specific cases, if 1H-Benzimidazole, 2-fluoro-is required, it should be carried out in a suitable laboratory environment and follow relevant safety regulations.
Nature:
-Appearance: 1H-Benzimidazole, 2-fluoro-is white to yellow crystal or crystal powder.
-Solubility: Its solubility in water is relatively low, but it can be dissolved in some organic solvents, such as ethanol, methanol and dichloromethane.
-Melting point: The melting point of 1H-Benzimidazole, 2-fluoro-is about 180-182 degrees Celsius.
Use:
-Pharmaceutical field: 1H-Benzimidazole, 2-fluoro-is an important intermediate compound that can be used to synthesize a variety of drugs and bioactive molecules. It has potential applications in the treatment of pathogenic microbial infections and the development of anti-cancer drugs.
-Pesticide field: The compound can also be used to prepare pesticides to protect plants from pathogens and insects.
Preparation Method:
The preparation method of 1H-Benzimidazole, 2-fluoro-can be obtained by reacting benzimidazole and fluorinated hydrocarbon. Specific steps are as follows:
1. The benzimidazole is dissolved in an appropriate organic solvent.
2. Add a fluorinated hydrocarbon, such as 2-fluoroethyl acetate or fluorobenzene.
3. Reaction at appropriate temperature and time conditions.
4. The product was obtained by filtration, and after proper treatment and purification, 1H-Benzimidazole, 2-fluoro-was obtained-.
Safety Information:
- 1H-Benzimidazole, 2-fluoro-is generally stable under normal conditions, but appropriate protective measures are still needed to avoid contact or inhalation.
-Wear appropriate protective gloves and eye protection when handling the compound to avoid skin contact and inhalation of gases, fumes or dust.
-It should be stored in a sealed container, away from fire and oxidizing agents, and avoid exposure to direct sunlight.
-Follow proper laboratory procedures and safety guidelines during handling and use.
Please note that the above information is for reference only. In specific cases, if 1H-Benzimidazole, 2-fluoro-is required, it should be carried out in a suitable laboratory environment and follow relevant safety regulations.
Last Update：2024-04-09 15:17:58
