2-fluoro-3-nitro-6-methylpyridine

2-fluoro-3-nitro-6-methylpyridine - Names and Identifiers

Name	2-Fluoro-6-methyl-3-nitropyridine
Synonyms	2-FLUORO-3-NITRO-6-PICOLINE 2-Fluoro-6-methyl-3-nitropyridine 2-FLUORO-6-METHYL-3-NITROPYRIDINE 2-fluoro-3-nitro-6-methylpyridine Pyridine, 2-fluoro-6-methyl-3-nitro-
CAS	19346-45-3
EINECS	251-156-6

2-fluoro-3-nitro-6-methylpyridine - Physico-chemical Properties

Molecular Formula	C6H5FN2O2
Molar Mass	156.11
Density	1.357±0.06 g/cm3(Predicted)
Melting Point	30℃
Boling Point	266.2±35.0 °C(Predicted)
Water Solubility	Slightly soluble in water.
Appearance	Solid
Color	Off-white
pKa	-3.74±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-fluoro-3-nitro-6-methylpyridine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

2-fluoro-3-nitro-6-methylpyridine - Introduction

The chemical formula is C7H5FN2O2, which is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
is a yellow crystalline solid. It has a fluorine atom and a methyl group substituted on the pyridine ring, and a nitro group substituted on the 3 position of the pyridine ring. It has a melting point of about 177-180 degrees Celsius and is stable at room temperature. This compound is insoluble in water, but soluble in organic solvents such as methanol, ethanol and dimethylformamide.

Use:
It is important in organic synthesis. It is often used as an intermediate in the synthesis of other organic compounds. In addition, it can also be used as dye intermediates, pharmaceutical intermediates and pesticide intermediates. It is also somewhat explosive due to the presence of its nitro functional group.

Method:
The preparation of calcium can be obtained by reacting pyridine with Methyl fluoride in the presence of sodium carbonate, followed by nitration. Specific preparation steps can refer to the relevant organic synthesis literature.

Safety Information:
Because it has a nitro functional group and may be explosive under some conditions, corresponding safety measures should be taken during operation. It may have an irritating effect on the eyes and skin, so direct contact should be avoided when in contact. At the same time, pay attention to moisture, fire and explosion protection during storage and transportation. For its specific use and handling, please follow the safety operation guidelines of the relevant chemicals and operate under the guidance of experienced personnel.

Last Update：2024-04-09 21:11:58