2-fluoro-5-methoxybenzaldehyde
2-fluoro-5-methoxybenzaldehyde
CAS: 105728-90-3
Molecular Formula: C8H7FO2
2-fluoro-5-methoxybenzaldehyde - Names and Identifiers
| Name | 2-fluoro-5-methoxybenzaldehyde |
| Synonyms | 6-FLUORO-M-ANISALDEHYDE Fluoro-5-Methoxybenzaldeh 2-FLUORO-5ETHOXYBENZALDEHYDE 2-FLUORO-5-METHOXYBENZALDEHYDE 2-fluoro-5-methoxybenzaldehyde Benzaldehyde,2-fluoro-5-methoxy- 4-Fluoro-3-formylanisole, 6-Fluoro-m-anisaldehyde |
| CAS | 105728-90-3 |
| EINECS | 600-676-2 |
| InChI | InChI=1/C5F9I/c6-1(2(7)15)3(8,4(9,10)11)5(12,13)14/b2-1+ |
| InChIKey | DKIQXHIAEMGZGO-UHFFFAOYSA-N |
2-fluoro-5-methoxybenzaldehyde - Physico-chemical Properties
| Molecular Formula | C8H7FO2 |
| Molar Mass | 154.14 |
| Density | 1.237 g/mL at 25 °C (lit.) |
| Melting Point | 48-50 °C |
| Boling Point | 229-230 °C (lit.) |
| Flash Point | 226°F |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 69.8mmHg at 25°C |
| BRN | 4379088 |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.532(lit.) |
2-fluoro-5-methoxybenzaldehyde - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29130000 |
| Hazard Class | IRRITANT |
2-fluoro-5-methoxybenzaldehyde - Introduction
2-Fluoro-5-methoxybenzaldehyde is an organic compound with the chemical formula C8H7FO2. The following is an introduction to the properties, uses, preparation methods and safety information of 2-fluoro-5-methoxybenzaldehyde:
Nature:
-Appearance: 2-Fluoro-5-methoxybenzaldehyde is a colorless to pale yellow solid.
-Melting point: about 75-80 degrees Celsius.
-Boiling point: about 204-206 degrees Celsius.
-Solubility: It has good solubility in polar solvents, such as ethanol and dichloromethane.
Use:
-2-Fluoro-5-methoxybenzaldehyde can be used as an important intermediate in organic synthesis. It can be used to synthesize a variety of compounds with applications such as pharmaceuticals, pesticides and dyes.
-In the pharmaceutical field, 2-fluoro-5-methoxybenzaldehyde can be used to synthesize certain anticancer drugs, antiviral drugs and antibacterial agents.
-In the field of pesticides, it can be used to prepare certain pesticides and herbicides.
-In the field of dyes, it can be used as a synthetic intermediate for some dyes of specific colors.
Preparation Method:
-A common method for preparing 2-fluoro-5-methoxybenzaldehyde is obtained by oxidizing 2-fluoro-5-methoxybenzoic acid. The reaction can be carried out using an oxidizing agent, such as chromium oxide (CrO3) or chromium trioxide (Cr2O3), under appropriate temperature and pH conditions.
Safety Information:
-2-Fluoro-5-methoxybenzaldehyde requires careful handling during use and storage to avoid contact with skin, eyes and respiratory tract.
-If taken by mistake or inhaled, seek medical help immediately.
-When preparing or operating, follow the relevant chemical safety procedures and wear appropriate protective equipment, such as laboratory gloves, protective glasses and masks.
Nature:
-Appearance: 2-Fluoro-5-methoxybenzaldehyde is a colorless to pale yellow solid.
-Melting point: about 75-80 degrees Celsius.
-Boiling point: about 204-206 degrees Celsius.
-Solubility: It has good solubility in polar solvents, such as ethanol and dichloromethane.
Use:
-2-Fluoro-5-methoxybenzaldehyde can be used as an important intermediate in organic synthesis. It can be used to synthesize a variety of compounds with applications such as pharmaceuticals, pesticides and dyes.
-In the pharmaceutical field, 2-fluoro-5-methoxybenzaldehyde can be used to synthesize certain anticancer drugs, antiviral drugs and antibacterial agents.
-In the field of pesticides, it can be used to prepare certain pesticides and herbicides.
-In the field of dyes, it can be used as a synthetic intermediate for some dyes of specific colors.
Preparation Method:
-A common method for preparing 2-fluoro-5-methoxybenzaldehyde is obtained by oxidizing 2-fluoro-5-methoxybenzoic acid. The reaction can be carried out using an oxidizing agent, such as chromium oxide (CrO3) or chromium trioxide (Cr2O3), under appropriate temperature and pH conditions.
Safety Information:
-2-Fluoro-5-methoxybenzaldehyde requires careful handling during use and storage to avoid contact with skin, eyes and respiratory tract.
-If taken by mistake or inhaled, seek medical help immediately.
-When preparing or operating, follow the relevant chemical safety procedures and wear appropriate protective equipment, such as laboratory gloves, protective glasses and masks.
Last Update：2024-04-09 15:17:50
