2-hydroxyphenylpropanone - Names and Identifiers
2-hydroxyphenylpropanone - Physico-chemical Properties
Molecular Formula | C9H10O2
|
Molar Mass | 150.17 |
Density | 1.118±0.06 g/cm3(Predicted) |
Melting Point | 15 °C |
Boling Point | 110 °C(Press: 1.0 Torr) |
pKa | 9.88±0.30(Predicted) |
Storage Condition | 2-8°C |
2-hydroxyphenylpropanone - Introduction
o-hydroxyphenylacetone, the chemical formula is C9H10O2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
o-hydroxyphenylacetone is a colorless to pale yellow liquid with the characteristic aroma of benzene ketones. It has a lower vapor pressure and a higher boiling point at room temperature, and is soluble in many organic solvents.
Use:
O-hydroxyphenylacetone is mainly used as an important intermediate in organic synthesis. It is widely used in the field of medicine to synthesize various drugs, including analgesics, anti-inflammatory drugs and anti-cancer drugs. In addition, it is also used in the preparation of fragrances, dyes and polymer additives.
Preparation Method:
o-hydroxyphenylacetone can be synthesized by a hydroxyl substitution reaction of p-hydroxyacetophenone. The commonly used synthetic method is the reaction of hydroxyacetophenone with alkyl halides under alkaline conditions to produce hydroxy-substituted products.
Safety Information:
O-hydroxyphenylacetone is relatively stable under normal operating conditions, but its vapor may be irritating to the eyes, respiratory system and skin. Rinse immediately with water when in contact with skin. Wear protective gloves, masks, and goggles for personal safety when handling the compound. At the same time, it should also be stored in a well-sealed container, away from fire and oxidizing agents. Please operate under suitable laboratory conditions and follow relevant safety guidelines.
Last Update:2024-04-09 21:11:58