2-methyl-4-(trifluoromethyl)pyrimidine

2-methyl-4-(trifluoromethyl)pyrimidine - Names and Identifiers

Name	2-methyl-4-(trifluoromethyl)pyrimidine
Synonyms	2-Methyl-6-trifluoromethylpyrimidine 2-methyl-4-(trifluoromethyl)pyrimidine 2-Methyl-4-(trifluoromethyl)pyrimidine 2-METHYL-6-TRIFLUOROMETHYLPYRIMIDIN-4-OL pyrimidine, 2-methyl-4-(trifluoromethyl)- 2-Methyl-6-(trifluoromethyl)-4-pyrimidinol 2-Methyl-6-(trifluoromethyl)pyrimidin-4-ol 4-pyrimidinol, 2-methyl-6-(trifluoromethyl)- 4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE 2-methyl-6-(trifluoromethyl)pyrimidin-4(1H)-one 2-Methyl-6-(trifluoromethyl)-4(3H)-pyrimidinone 2-Methyl-6-(trifluoromethyl)pyrimidin-4(3H)-one 2-methyl-6-(trifluoromethyl)-1H-pyrimidin-4-one 2-methyl-6-(trifluoromethyl)-1,4-dihydropyrimidin-4-one
CAS	2836-44-4
InChI	InChI=1/C6H5F3N2/c1-4-10-3-2-5(11-4)6(7,8)9/h2-3H,1H3

2-methyl-4-(trifluoromethyl)pyrimidine - Physico-chemical Properties

Molecular Formula	C6H5F3N2O
Molar Mass	178.11
Density	1.47
Melting Point	141.0 to 145.0 °C
Boling Point	149℃
Flash Point	44℃
Vapor Presure	6.886mmHg at 25°C
pKa	6.83±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.427

2-methyl-4-(trifluoromethyl)pyrimidine - Risk and Safety

Risk Codes	20/22 - Harmful by inhalation and if swallowed.
Safety Description	36/37 - Wear suitable protective clothing and gloves.
HS Code	29335990

2-methyl-4-(trifluoromethyl)pyrimidine - Introduction

2-methyl-4-(trifluoromethyl)pyrimidine is an organic compound with the molecular formula C6H5F3N2O and a molecular weight of 174.12g/mol.

Nature:
2-methyl-4-(trifluoromethyl)pyrimidine is a colorless to pale yellow solid, flammable. It is stable at room temperature, not easily soluble in water, soluble in organic solvents such as ethanol and dimethyl sulfoxide.

Use:
2-methyl-4-(trifluoromethyl)pyrimidine has a wide range of applications in drug synthesis and pesticide manufacturing. For example, it can be used in the synthesis of antitumor drugs, antibacterial drugs, plant growth regulators, etc. In addition, it can also be used as a synthetic raw material for fluorine-containing organic compounds.

Method:
The synthesis of 2-methyl-4-(trifluoromethyl)pyrimidine can be obtained by reacting 2-methyl-4-hydroxyl pyrimidine with trifluoromethyl sulfonyl fluoride. Specific synthetic steps can refer to the chemical synthesis literature.

Safety Information:
2-methyl-4-(trifluoromethyl)pyrimidine specific safety information need to see the Chemical Safety Data Sheet (MSDS) to understand. It may be irritating to the eyes, skin and respiratory tract, so care should be taken when using it, such as wearing appropriate protective equipment.

Last Update：2024-04-09 20:52:54