2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole
2-Methyl-2H-indazole-6-boronic acid pinacol ester
CAS: 1204580-79-9
Molecular Formula: C14H19BN2O2
2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole - Names and Identifiers
2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole - Physico-chemical Properties
| Molecular Formula | C14H19BN2O2 |
| Molar Mass | 258.13 |
| Density | 1.11±0.1 g/cm3(Predicted) |
| Boling Point | 404.4±18.0 °C(Predicted) |
| pKa | 1.03±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD11109435 |
2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indazole - Introduction
Acid pinacol ester (acid pinacol ester) is an organic compound. Its properties are as follows:
1. Appearance: white or almost white crystal
2. molecular formula: C15H21BN2O2
3. Molecular weight: 283.15g/mol
4. Melting point: 119-121°C
5. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM).
Acid pinacol ester is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used to build C- N keys, C- O keys, and C- C keys. Specific application fields include drug synthesis, polymer synthesis, and ligand synthesis.
the method of preparing acid pinacol ester is as follows:
First, pyridine and 2-methylindole are heated in an inert atmosphere to produce 2-methyl-2H-indazole. This compound is then reacted with 4-hydro -4,4,5, 5-tetramethyl -1,3, 2-dioxaborolane in the presence of dilute sulfuric acid to give the oxadiazepine pinacol.
Regarding safety information, because the toxicity and danger of acid pinacol ester have not been fully studied, care should be taken in contact and use. When using the compound, follow laboratory safety procedures and take necessary precautions, such as wearing gloves, goggles and laboratory clothing. It is recommended to use the compound under professional guidance or operator guidance and to comply with relevant safety and environmental regulations.
1. Appearance: white or almost white crystal
2. molecular formula: C15H21BN2O2
3. Molecular weight: 283.15g/mol
4. Melting point: 119-121°C
5. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM).
Acid pinacol ester is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used to build C- N keys, C- O keys, and C- C keys. Specific application fields include drug synthesis, polymer synthesis, and ligand synthesis.
the method of preparing acid pinacol ester is as follows:
First, pyridine and 2-methylindole are heated in an inert atmosphere to produce 2-methyl-2H-indazole. This compound is then reacted with 4-hydro -4,4,5, 5-tetramethyl -1,3, 2-dioxaborolane in the presence of dilute sulfuric acid to give the oxadiazepine pinacol.
Regarding safety information, because the toxicity and danger of acid pinacol ester have not been fully studied, care should be taken in contact and use. When using the compound, follow laboratory safety procedures and take necessary precautions, such as wearing gloves, goggles and laboratory clothing. It is recommended to use the compound under professional guidance or operator guidance and to comply with relevant safety and environmental regulations.
Last Update：2024-04-09 21:04:16
