2-methylpyridin-4(1H)-one
4-Hydroxy-2-methylpyridine
CAS: 18615-86-6
Molecular Formula: C6H7NO
2-methylpyridin-4(1H)-one - Names and Identifiers
| Name | 4-Hydroxy-2-methylpyridine |
| Synonyms | 2-METHYL-PYRIDIN-4-OL 4-Pyridinol, 2-methyl- 2-methylpyridin-4(1H)-one 2-Methyl-4-hydroxy-pyridin 2-Methyl-4-hydroxypyridine 4-HYDROXY-2-METHYLPYRIDINE 4-Hydroxy-2-methylpyridine 4-Hydroxy-2-methylpyridine nitrate |
| CAS | 18615-86-6 |
| EINECS | 695-114-6 |
| InChI | InChI=1/C6H7NO/c1-5-4-6(8)2-3-7-5/h2-4H,1H3,(H,7,8) |
2-methylpyridin-4(1H)-one - Physico-chemical Properties
| Molecular Formula | C6H7NO |
| Molar Mass | 109.13 |
| Density | 1.120±0.06 g/cm3(Predicted) |
| Melting Point | 174-176 °C(Solv: acetone (67-64-1)) |
| Boling Point | 350-360 °C |
| Flash Point | 98.2°C |
| Vapor Presure | 0.312mmHg at 25°C |
| Appearance | Bright yellow solid |
| pKa | 5.36±0.18(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.499 |
| MDL | MFCD04114156 |
2-methylpyridin-4(1H)-one - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29339900 |
2-methylpyridin-4(1H)-one - Introduction
4-hydroxy-2-methylpyriridine (abbreviated as 4-hydroxy-2-methylpyriridine, abbreviated as 4-HMP) is an organic compound with the chemical formula C6H7NO. The following is a description of the nature, use, method and safety information of 4-HMP:
Nature:
-Appearance: 4-HMP is a colorless to pale yellow liquid or solid crystal.
-Solubility: Soluble in water, alcohols and ethers, slightly soluble in non-polar solvents such as petroleum ether.
-Melting point: About 45-47 degrees Celsius.
-Stability: relatively stable at room temperature, oxidation reaction may occur in light and air.
Use:
-As an intermediate: 4-HMP can be used to synthesize a variety of organic compounds.
-Chemical reagent: 4-HMP can be used as a reagent and catalyst in organic synthesis.
Method:
The preparation method of-4-HMP can be obtained by the oxidation reaction of pyridine compounds. A commonly used synthesis method is the catalytic reaction of pyridine with methanol in an oxygen atmosphere to give 4-HMP.
Safety Information:
- 4-HMP may be irritating to the skin, eyes and respiratory system. When handling, avoid exposure to the skin, eyes and respiratory tract, and take appropriate protective measures, such as wearing gloves, goggles and masks.
-When using 4-HMP, pay attention to follow the safety operation procedures and ensure that it is operated in a well-ventilated place.
- 4-HMP should be stored in a cool, dry, well-ventilated place, and away from fire and oxidizing agents.
-During use, avoid contacting 4-HMP with strong oxidants or acidic substances to avoid possible dangerous reactions.
In General, 4-Hydroxy-2-methylpyridine is a commonly used organic synthesis intermediate and reagent, and has a wide range of applications in the fields of synthetic chemistry and organic synthesis. However, when using it, it is necessary to pay attention to its potential irritation and safety risks.
Nature:
-Appearance: 4-HMP is a colorless to pale yellow liquid or solid crystal.
-Solubility: Soluble in water, alcohols and ethers, slightly soluble in non-polar solvents such as petroleum ether.
-Melting point: About 45-47 degrees Celsius.
-Stability: relatively stable at room temperature, oxidation reaction may occur in light and air.
Use:
-As an intermediate: 4-HMP can be used to synthesize a variety of organic compounds.
-Chemical reagent: 4-HMP can be used as a reagent and catalyst in organic synthesis.
Method:
The preparation method of-4-HMP can be obtained by the oxidation reaction of pyridine compounds. A commonly used synthesis method is the catalytic reaction of pyridine with methanol in an oxygen atmosphere to give 4-HMP.
Safety Information:
- 4-HMP may be irritating to the skin, eyes and respiratory system. When handling, avoid exposure to the skin, eyes and respiratory tract, and take appropriate protective measures, such as wearing gloves, goggles and masks.
-When using 4-HMP, pay attention to follow the safety operation procedures and ensure that it is operated in a well-ventilated place.
- 4-HMP should be stored in a cool, dry, well-ventilated place, and away from fire and oxidizing agents.
-During use, avoid contacting 4-HMP with strong oxidants or acidic substances to avoid possible dangerous reactions.
In General, 4-Hydroxy-2-methylpyridine is a commonly used organic synthesis intermediate and reagent, and has a wide range of applications in the fields of synthetic chemistry and organic synthesis. However, when using it, it is necessary to pay attention to its potential irritation and safety risks.
Last Update：2024-04-10 22:29:15
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