2-nitro-4-(trifluoromethoxy)aniline
2-nitro-4-(trifluoromethoxy)aniline
CAS: 2267-23-4
Molecular Formula: C7H5F3N2O3
2-nitro-4-(trifluoromethoxy)aniline - Names and Identifiers
| Name | 2-nitro-4-(trifluoromethoxy)aniline |
| Synonyms | 2-Nitro-4-(trifluoromethoxy)aniline 2-NITRO-4-(TRIFLUOROMETHOXY)ANILINE 2-nitro-4-(trifluoromethoxy)aniline 3-Nitro-4-aminotrifluoromethoxybenzene Benzenamine, 2-nitro-4-(trifluoromethoxy)- 1-Amino-2-nitro-4-(trifluoromethoxy)benzene 2-Amino-5-(trifluoromethoxy)nitrobenzene, 4-Amino-3-nitro-alpha,alpha,alpha-trifluoroanisole |
| CAS | 2267-23-4 |
| InChI | InChI=1/C7H5F3N2O3/c8-7(9,10)15-4-1-2-5(11)6(3-4)12(13)14/h1-3H,11H2 |
| InChIKey | YCGFVAPIBALHRT-UHFFFAOYSA-N |
2-nitro-4-(trifluoromethoxy)aniline - Physico-chemical Properties
| Molecular Formula | C7H5F3N2O3 |
| Molar Mass | 222.12 |
| Density | 1.543±0.06 g/cm3(Predicted) |
| Melting Point | 62 °C |
| Boling Point | 284.3±35.0 °C(Predicted) |
| Flash Point | 125.7°C |
| Vapor Presure | 0.00301mmHg at 25°C |
| pKa | -1.38±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Sensitive | Light Sensitive |
| Refractive Index | 1.525 |
2-nitro-4-(trifluoromethoxy)aniline - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S23 - Do not breathe vapour. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
2-nitro-4-(trifluoromethoxy)aniline - Introduction
2-nitro-4-(trifluoromethoxy)aniline is an organic compound with the chemical formula C7H5F3N2O3. Its main properties are as follows:
1. Appearance: White crystalline solid.
2. Melting Point: about 109-111 ℃.
3. Boiling point: About 324-326 ℃.
4. Solubility: It is easy to dissolve in non-polar solvents such as chloroform and ethanol, but it is less soluble in water.
The main uses of 2-nitro-4-(trifluoromethoxy)aniline include:
1. Chemical reagents: commonly used in organic synthesis reactions as reagents or intermediates.
2. Pesticide Research: can be used as pesticide raw materials or intermediates.
3. Fluorescent dye: with fluorescent properties, can be used as a fluorescent dye synthesis.
A common method for preparing 2-nitro-4-(trifluoromethoxy)aniline is through the reaction of 2-nitrophenol with trifluoromethane anhydride under alkaline conditions. The reaction generally requires appropriate solvents and temperatures and is carried out under a protective atmosphere.
Regarding the safety information of 2-nitro-4-(trifluoromethoxy)aniline, the following matters need to be paid attention:
1. Toxicity: this compound may have certain toxicity to the environment and human body.
2. Irritation: can be irritating to the eyes and skin, and should be protected when in contact.
3. Flammability: 2-nitro-4-(trifluoromethoxy)aniline is a combustible substance and should be kept away from open flames and high temperatures.
4. Storage and handling: should be stored in a cool, dry, well-ventilated place, avoid direct sunlight. When handling, it is necessary to wear personal protective equipment and carry out good laboratory operations.
When handling this compound, please make sure to follow the correct operating procedures and follow appropriate safety procedures.
1. Appearance: White crystalline solid.
2. Melting Point: about 109-111 ℃.
3. Boiling point: About 324-326 ℃.
4. Solubility: It is easy to dissolve in non-polar solvents such as chloroform and ethanol, but it is less soluble in water.
The main uses of 2-nitro-4-(trifluoromethoxy)aniline include:
1. Chemical reagents: commonly used in organic synthesis reactions as reagents or intermediates.
2. Pesticide Research: can be used as pesticide raw materials or intermediates.
3. Fluorescent dye: with fluorescent properties, can be used as a fluorescent dye synthesis.
A common method for preparing 2-nitro-4-(trifluoromethoxy)aniline is through the reaction of 2-nitrophenol with trifluoromethane anhydride under alkaline conditions. The reaction generally requires appropriate solvents and temperatures and is carried out under a protective atmosphere.
Regarding the safety information of 2-nitro-4-(trifluoromethoxy)aniline, the following matters need to be paid attention:
1. Toxicity: this compound may have certain toxicity to the environment and human body.
2. Irritation: can be irritating to the eyes and skin, and should be protected when in contact.
3. Flammability: 2-nitro-4-(trifluoromethoxy)aniline is a combustible substance and should be kept away from open flames and high temperatures.
4. Storage and handling: should be stored in a cool, dry, well-ventilated place, avoid direct sunlight. When handling, it is necessary to wear personal protective equipment and carry out good laboratory operations.
When handling this compound, please make sure to follow the correct operating procedures and follow appropriate safety procedures.
Last Update：2024-04-10 22:29:15
