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2-pinene

alpha-pinene

CAS: 2437-95-8;80-56-8

Molecular Formula: C10H16

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2-pinene - Names and Identifiers

Name alpha-pinene
Synonyms un2368
2-pinene
α-Pinene
A-PINENE
ai3-24594
FEMA 2902
ACINTENE A
acintene a
ALFA-PINENE
DL-A-PINENE
alpha-pinene
monoterpenes
pinene isomer
pinene, alpha
2-pinene (8ci)
dl-pin-2(3)-ene
DL-ALPHA-PINENE
CYCLIC DEXADIENE
fema number 2902
pinene (dl-alpha)
alpha-pinene (natural)
4,6,6-trimethylbicyklo(3,1,1)hept-3-en
2,6,6-trimethylbicyclo(3.1.1)hept-2-ene
alpha-pinene [un2368] [flammable liquid]
bicyclo(3.1.1)hept-2-ene, 2,6,6-trimethyl
2,6,6-trimethylbicyclo(3.1.1)-2-hept-2-ene
bicyclo(3.1.1)hept-2-ene, 2,6,6-trimethyl-
BICYCLO [3.1.1] HEPT-2-ENE, 2,6,6-TRIMETHYL
4-05-00-00456 (beilstein handbook reference)
4,6,6-trimethylbicyklo(3,1,1)hept-3-en [czech]
(1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
CAS 2437-95-8
80-56-8
EINECS 219-445-9
InChI InChI=1/C10H16/c1-7-4-5-8-6-9(7)10(8,2)3/h4,8-9H,5-6H2,1-3H3/t8-,9-/m0/s1

2-pinene - Physico-chemical Properties

Molecular FormulaC10H16
Molar Mass136.23
Density0.858g/mLat 25°C(lit.)
Melting Point-55 °C
Boling Point155-156°C(lit.)
Flash Point90°F
Water Solubilityinsoluble
Vapor Presure3.49mmHg at 25°C
Refractive Indexn20/D 1.465(lit.)
Physical and Chemical PropertiesThe main component of turpentine oil was 86% in Pinus massoniana turpentine. Colorless transparent liquid, with the unique odor of the pine.
melting point -102.2 ℃
boiling point 155~156.2 ℃
relative density 0.8582~0.8592
refractive index 1.4658~1.4664
solubility insoluble in water, soluble in ethanol, ether, acetic acid and other organic solvents, soluble in rosin.
UseUsed as a solvent for paint, wax, etc., and raw materials for the preparation of pinene, terpineol, borneol, synthetic camphor, synthetic resin, etc.

2-pinene - Risk and Safety

Risk CodesR10 - Flammable
R36/37/38 - Irritating to eyes, respiratory system and skin.
R43 - May cause sensitization by skin contact
R50 - Very Toxic to aquatic organisms
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. 
UN IDsUN 2368 3/PG 3
WGK Germany1
RTECSDT7000000
HS Code29021910

2-pinene - Upstream Downstream Industry

Raw MaterialsOil of turpentine
Oil of turpentine
Downstream ProductsCamphene
2,6-Dimethyloct-7-en-2-ol

2-pinene - Nature

Open Data Verified Data

There are two kinds of isomers of a pinene and beta ENE. Pinene is the main component of turpentine, accounting for 86% in Pinus massoniana turpentine. Β pinene is a secondary component of turpentine, accounting for 5% in Pinus massoniana turpentine. Colorless transparent liquid, with the unique odor of the pine, there are left, right, racemic three. Insoluble in water, soluble in ethanol, ether, acetic acid and other organic solvents, soluble in rosin.

Last Update:2024-01-02 23:10:35

2-pinene - Preparation Method

Open Data Verified Data

obtained by fractional distillation of turpentine under reduced pressure.

Last Update:2022-01-01 10:38:39

2-pinene - Use

Open Data Verified Data

important organic synthesis raw materials, can be used for the synthesis of a series of perfume products, as well as synthetic camphor, borneol, etc.; Pinene by ozone oxidation of pinone acid, and then further oxidation of gallic acid, thus, plant growth stimulating hormone, synthetic lubricant, plasticizer, etc. can be prepared; Pinene can also be
Made of pinene resin, etc.; Can also be used as a solvent such as lacquer wax.

Last Update:2022-01-01 10:38:39

2-pinene - Safety

Open Data Verified Data

This product is non-toxic. In case of high temperature, open flame, oxidant combustion risk. Should be stored in a cool, ventilated place, away from the flame heat source, to prevent sun exposure, and oxidant (including nitric acid) stored separately, packaging to be sealed, handling light light unloading, to prevent damage. Is Class II flammable liquid, railway Code No. 62055.

Last Update:2022-01-01 10:38:40

2-pinene - Reference Information

Open Data Unverified Data
effect 1, anti-tumor effect
Zhang Z et al. in the study of the effect of α-pinene on non-small cell lung cancer, α-pinene combined with paclitaxel to treat A549 cells, through the combination of drugs can increase the effect of paclitaxel on tumor inhibition. The results showed that α-pinene could significantly promote tumor cell apoptosis. This is mainly due to the synergistic effect when combined with paclitaxel. Further research mechanism shows that when α-pinene is combined with paclitaxel, the proportion of G0/G1 phase cells can be significantly increased, and there are changes in cell morphology, such as chromatin condensation, nuclear fragmentation and other changes, to lead to the production of tumor cell apoptosis.
2, antifungal effect
the main components in the cell wall of Candida albicans are chitin, glucose and mannan, the chemical composition in the cell membrane is mainly ergosterol, nucleic acid is mainly DNA, a small amount of RNA. The synthesis of these components can lead to the death of bacterial cells. Xia Zhongdi and others found that α-pinene has obvious inhibition on the synthesis of chitin and polysaccharide components in the cell wall of Candida albicans, the synthesis of ergosterol in the cell membrane and the synthesis of nucleic acid DNA and RNA. Among them, the inhibition of ergosterol synthesis is more obvious. Pichette A and other studies also found that α-pinene has anti-inflammatory, antibacterial and antioxidant effects.
3. Anti-allergic and ulcer improvement
In Nam SY et al.'s study on the inhibitory effect of α-pinene on allergic rhinitis in mice, it was found that the expression of IL-4 in spleen lymphocytes was reduced, and IgE, α-TNF, ICAM-1 and macrophage inflammatory protein -2 in nasal mucosa were reduced. Increased eosinophils and mast cells in mice were also significantly reduced after α-pinene treatment. In addition, in the study of α-pinene on the HMC-1 of human mast cell lines, α-pinene can inhibit the activities of phosphorylated RIP2, IKK-β, NF-κB and caspase-1 after sensitization. Therefore, α-pinene is considered as an antiallergic agent.
in the study of improving ulcer, α-pinene extracted from Mde A et al. was Pinheiro to treat gastric ulcer in mice, and it was found that α-pinene has significant anti-ulcer activity.
Application Used for the synthesis of linalool, nerol, geraniol, laurenol and its esters, norfenol, norfenol acetate, citral, ionone, citronellol and aldehydes, hydroxycitronellal and its esters, neogluraldehyde, neoglurinonitrile, longdanone, terene resin, etc. It is an important raw material for synthesizing spices and flavors.
Last Update:2024-04-12 11:19:16
2-pinene
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Jiangxi Cedar natural medicinal oil Co., LTD
Featured ProductsMultiple SpecificationsSpot supply
Product Name: alpha-Pinene Visit Supplier Webpage Request for quotation
CAS: 80-56-8
Tel: 18000738807
Email: 2134411736@qq.com
Mobile: 18000738807
QQ: 2134411736 Click to send a QQ message
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: alpha-pinene Request for quotation
CAS: 2437-95-8/80-56-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Spot supply
Product Name: alpha-pinene Request for quotation
CAS: 2437-95-8
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: alpha-pinene Request for quotation
CAS: 2437-95-8/80-56-8
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685 Click to send a QQ messageSend QQ message
Wechat: chemical6666
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: alpha-pinene Request for quotation
CAS: 2437-95-8
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Wechat: chemical6666 
MedChemExpress (MCE)
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CAS: 80-56-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Multiple SpecificationsSpot supply
Product Name: α-Pinene Visit Supplier Webpage Request for quotation
CAS: 80-56-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: α-Pinene Visit Supplier Webpage Request for quotation
CAS: 80-56-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: alpha-pinene Request for quotation
CAS: 80-56-8
Tel: 0086-551-65418684
Email: sales@tnjchem.com
     info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
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View History
2-pinene
Piperidinium,1-ethyl-1-propyl-, bromide (1:1)
H-4-NITRO-PHE-OET HCL
IMIDAZOLE-4-ACETIC ACID MONOHYDROCHLORIDE
Raw Materials for 2-pinene
Oil of turpentine
Oil of turpentine
Downstream Products for 2-pinene
Camphene
2,6-Dimethyloct-7-en-2-ol
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