2-tert-butoxycarbonylamino-3-methylpyridine

2-tert-butoxycarbonylamino-3-methylpyridine - Names and Identifiers

Name	2-(BOC-AMINO)-3-METHYLPYRIDINE
Synonyms	BUTTPARK 9250-22 2-BOC-Amino-3-picoline N-Boc-3-methylpyridin-2-amine 2-(BOC-AMINO)-3-METHYLPYRIDINE N-Boc-3-isopropylpyridin-2-amine t-Butyl 3-methylpyridin-2-ylcarbamate Carbamic acid, (3-methyl-2-pyridinyl)- tert-butyl (3-methylpyridin-2-yl)carbamate 2-tert-butoxycarbonylamino-3-methylpyridine tert-butyl N-(3-Methylpyridin-2-yl)carbaMate (3-METHYLPYRIDINE-2-YL)CARBAMIC ACID TERT-BUTYL ESTER Carbamic acid, N-(3-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester Carbamic acid, (3-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
CAS	138343-75-6
InChI	InChI=1/C11H16N2O2/c1-8-6-5-7-12-9(8)13-10(14)15-11(2,3)4/h5-7H,1-4H3,(H,12,13,14)
InChIKey	MJPLUXLNYQHWIU-UHFFFAOYSA-N

2-tert-butoxycarbonylamino-3-methylpyridine - Physico-chemical Properties

Molecular Formula	C11H16N2O2
Molar Mass	208.26
Density	1.108±0.06 g/cm3(Predicted)
Melting Point	134-138 °C (lit.)
Boling Point	268.5±28.0 °C(Predicted)
Flash Point	116.195°C
Vapor Presure	0.008mmHg at 25°C
pKa	12.56±0.70(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.541
Physical and Chemical Properties	WGK Germany:3

2-tert-butoxycarbonylamino-3-methylpyridine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

2-tert-butoxycarbonylamino-3-methylpyridine - Introduction

2-(BOC-amino)-3-methylpyridine is an organic compound containing methyl and pyridine rings in its structure, and a Boc-amino group (tert-butylpropionate amino group) is inserted at the 2-position. Here is some information about 2-(BOC-amino)-3-methylpyridine:

Nature:
-Appearance: Colorless or white crystalline solid
-Molecular formula: C12H19NO2
-Molecular weight: 209.29g/mol
-Melting point: 58-59°C
-Boiling Point: 305°C (at 760 mmHg)
-Solubility: 2-(BOC-amino)-3-picoline is soluble in most common organic solvents, such as ether, methanol and dimethyl sulfoxide.

Use:
- 2-(BOC-amino)-3-methylpyridine is a common organic synthesis intermediate.
-It can be used to prepare various bioactive molecules, pharmaceutical intermediates and functional materials.

Preparation Method:
The synthesis of -2-(BOC-amino)-3-methylpyridine is usually carried out by first synthesizing 3-methylpyridine and then inserting the Boc-amino group into the 2-position.
-The specific synthesis method can be adjusted according to literature and laboratory conditions.

Safety Information:
- 2-(BOC-amino)-3-methylpyridine is generally less dangerous under conventional conditions of use.
-However, it is still recommended to follow laboratory safety procedures during use, such as wearing chemical protective gloves, goggles and laboratory breathing equipment to avoid skin contact and inhalation.
-When handling and storing, keep it away from fire and oxidizing agents, and avoid contact with strong acids and strong bases.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. If necessary, please consult the relevant institutions or professionals.

Last Update：2024-04-09 19:05:46