2-trifluoromethyl-3-Aminopyridine
2-trifluoromethyl-3-Aminopyridine
CAS: 106877-32-1
Molecular Formula: C6H5F3N2
2-trifluoromethyl-3-Aminopyridine - Names and Identifiers
| Name | 2-trifluoromethyl-3-Aminopyridine |
| Synonyms | 3-Amino-2-(trifluoromethyl)pyr 2-trifluoromethyl-3-Aminopyridine 2-TRIFLUOROMETHYL-3-AMINOPYRIDINE 3-Amino-2-trifluoromethylpyridine 2-(Trifluoromethyl)-3-pyridinamine 2-(trifluoromethyl)pyridin-3-amine 2-(TrifluoroMethyl)-3-aMinopyridine 3-Amino-2-(trifluoromethyl)-Pyridine 3-PyridinaMine, 2-(trifluoroMethyl)- 3-AMINO-2-(TRIFLUOROMETHYL)-PYRIDINE |
| CAS | 106877-32-1 |
| InChI | InChI=1/C6H5F3N2/c7-6(8,9)5-4(10)2-1-3-11-5/h1-3H,10H2 |
| InChIKey | XZKZVCLLDKWOKM-UHFFFAOYSA-N |
2-trifluoromethyl-3-Aminopyridine - Physico-chemical Properties
| Molecular Formula | C6H5F3N2 |
| Molar Mass | 162.11 |
| Density | 1.368±0.06 g/cm3(Predicted) |
| Melting Point | 68-72 °C |
| Boling Point | 221.2±35.0 °C(Predicted) |
| Flash Point | 87.589°C |
| Vapor Presure | 0.108mmHg at 25°C |
| pKa | 1.49±0.22(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.479 |
2-trifluoromethyl-3-Aminopyridine - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
2-trifluoromethyl-3-Aminopyridine - Introduction
3-amino -2-(trifluoromethyl) pyridine, chemical formula C6H4F3N2, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
3-Amino -2-(trifluoromethyl) pyridine is a colorless to light yellow solid with a pyridine-like odor. It is relatively stable and soluble in water and organic solvents at room temperature. It is a basic compound that reacts with acids to form the corresponding salts.
Use:
3-amino -2-(trifluoromethyl) pyridine has a wide range of applications in organic synthesis. It is useful as a ligand, buffer, catalyst, and intermediate. Its application in the field of drug research and development is also common.
Preparation Method:
3-Amino -2-(trifluoromethyl) pyridine can be synthesized in a variety of ways. A common synthetic method is to react pyridine with a trifluoromethylation reagent to obtain the target compound by a trifluoromethylation reaction. The specific synthesis method will be optimized according to actual needs and conditions.
Safety Information:
3-amino -2-(trifluoromethyl) pyridine has certain safety under general operating conditions. However, as with all chemicals, there are still some safety precautions to follow. Wear appropriate personal protective equipment to avoid inhalation, ingestion and skin contact. Avoid contact with oxidants, strong acids or strong bases during handling and storage. In case of accidental contact or inhalation, seek medical attention immediately.
Nature:
3-Amino -2-(trifluoromethyl) pyridine is a colorless to light yellow solid with a pyridine-like odor. It is relatively stable and soluble in water and organic solvents at room temperature. It is a basic compound that reacts with acids to form the corresponding salts.
Use:
3-amino -2-(trifluoromethyl) pyridine has a wide range of applications in organic synthesis. It is useful as a ligand, buffer, catalyst, and intermediate. Its application in the field of drug research and development is also common.
Preparation Method:
3-Amino -2-(trifluoromethyl) pyridine can be synthesized in a variety of ways. A common synthetic method is to react pyridine with a trifluoromethylation reagent to obtain the target compound by a trifluoromethylation reaction. The specific synthesis method will be optimized according to actual needs and conditions.
Safety Information:
3-amino -2-(trifluoromethyl) pyridine has certain safety under general operating conditions. However, as with all chemicals, there are still some safety precautions to follow. Wear appropriate personal protective equipment to avoid inhalation, ingestion and skin contact. Avoid contact with oxidants, strong acids or strong bases during handling and storage. In case of accidental contact or inhalation, seek medical attention immediately.
Last Update：2024-04-09 20:45:29
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