2-氨基-5-氯吡啶
2-Amino-5-chloropyridine
CAS: 1072-98-6
Molecular Formula: C5H5ClN2
2-氨基-5-氯吡啶 - Names and Identifiers
| Name | 2-Amino-5-chloropyridine |
| Synonyms | 5-chloropyridin-2-amine 5-chloro-2-pyridylamine 5-Chloro-2-pyridinamine 2-Amino-5-chlorophridine 5-Chloro-a-aminopyridine 2-Amino-5-chloropyridine 5-Chloro-2-pyridineamine 2-amino-5-chloropyridinium 2-AMINO-5-CHLOROPYRIDINE FOR SYNTHESIS 2-AMINO-5-CHLOROPYRIDINE 5-CHLORO-PYRIDIN-2-YLAMINE |
| CAS | 1072-98-6 |
| EINECS | 214-020-4 |
| InChI | InChI=1/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)/p+1 |
| InChIKey | MAXBVGJEFDMHNV-UHFFFAOYSA-N |
2-氨基-5-氯吡啶 - Physico-chemical Properties
| Molecular Formula | C5H5ClN2 |
| Molar Mass | 128.56 |
| Density | 1.2417 (rough estimate) |
| Melting Point | 135-138 °C (lit.) |
| Boling Point | 127-128 °C/11 mmHg (lit.) |
| Flash Point | 160 °C |
| Water Solubility | 1 g/L (20 ºC) |
| Solubility | Soluble in water and ethanol |
| Vapor Presure | 0.0142mmHg at 25°C |
| Appearance | White-like powder crystal |
| Color | Beige to beige-brown |
| BRN | 108735 |
| pKa | 4.67±0.13(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | `sensitive` to light and air |
| Refractive Index | 1.5110 (estimate) |
| MDL | MFCD00006324 |
| Physical and Chemical Properties | Melting point 134-138°C boiling point 127-128°C (11 mmHg) flash point 160°C water-soluble 1g/L (20°C) |
| Use | For the production of herbicides, drugs such as zopiclone |
2-氨基-5-氯吡啶 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29333999 |
| Hazard Note | Harmful |
| Hazard Class | IRRITANT |
2-氨基-5-氯吡啶 - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | 2-amino -5-chloropyridine is uncrystalline in white powder and can be used as an intermediate in organic synthesis. |
| application | 2-amino-5-chloropyridine is a pyridine organic substance, which can be used to produce herbicides, drugs zopiclone, and organic synthesis. |
| Synthesis method | Through the structural analysis of 2-amino-5-chloropyridine compounds, the synthesis route was designed. 2-Amino-5-chloropyridine was prepared from 2-aminopyridine. The target compound is prepared by nitration, amidation, and reduction reactions. The synthesis reaction formula of 2-amino -5-chloropyridine is as follows: |
| Uses | 5-chloro-2-pyridinamide is a useful synthetic intermediate. It can be used for the synthesis of the non-benzodiazepine GABAA receptor agonist cyclopyryrone. Production of herbicides, drug zopiclone, organic synthesis. |
Last Update：2024-04-09 20:49:11
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View History
2-氨基-5-氯吡啶
Bis(stearic acid) cobalt(II) salt
ZM 306416 HYDROCHLORIDE
1-醛基哌啶-4-甲酸
RARECHEM AL CF 0941
4-((2-forMylphenoxy)Methyl)benzoic acid
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γ-氨基丁酸受体亚基β-1
2-苯乙基溴
2-丙烯-1-胺与环氧氯丙烷的聚合物盐酸盐
Bis(stearic acid) cobalt(II) salt
ZM 306416 HYDROCHLORIDE
1-醛基哌啶-4-甲酸
RARECHEM AL CF 0941
4-((2-forMylphenoxy)Methyl)benzoic acid
tert-Butyl 3-(acetoxymethyl)-4-hydroxypyrrolidine- 1-carboxylate...
γ-氨基丁酸受体亚基β-1
2-苯乙基溴
2-丙烯-1-胺与环氧氯丙烷的聚合物盐酸盐