2-氯-4-三氟甲基-5-羧基噻唑

2-氯-4-三氟甲基-5-羧基噻唑 - Names and Identifiers

Name	2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid
Synonyms	2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid 2-Chloro-4-(Trifluoromethyl)-5-Thiazolecarboxylic Acid 2-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID 5-Thiazolecarboxylicacid, 2-chloro-4-(trifluoroMethyl)- 2-chloro-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid
CAS	72850-61-4
EINECS	1533716-785-6

2-氯-4-三氟甲基-5-羧基噻唑 - Physico-chemical Properties

Molecular Formula	C5HClF3NO2S
Molar Mass	231.58
Density	1.779±0.06 g/cm3(Predicted)
Melting Point	131-135 °C(Solv: hexane (110-54-3); benzene (71-43-2))
Boling Point	337.4±52.0 °C(Predicted)
pKa	1.57±0.36(Predicted)
Storage Condition	2-8°C

2-氯-4-三氟甲基-5-羧基噻唑 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

2-氯-4-三氟甲基-5-羧基噻唑 - Introduction

2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid, the chemical formula is C6H2ClF3N2O2S, and the molecular weight is 232.61g/mol.

Nature:
2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid is a colorless to pale yellow solid powder. It is stable at room temperature and has low solubility. The compound has a bitter taste and a pungent odor.

Use:
2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid has a wide range of applications in the field of medicine. It can be used as an intermediate of antibacterial, antifungal and antitumor drugs, and has cell proliferation inhibition and anti-inflammatory effects. In addition, it can also be used as a reagent in the synthesis of pesticides and organic synthesis reactions.

Preparation Method:
2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid can be prepared by reacting 2-chloro-4-trifluoromethylthiazole with chloroacetic acid.

Safety Information:
2-Chloro-4-(trifluoromethyl)thiazole-5-carboxylic acid is irritating and contact with skin and eyes may cause irritation and burns. Appropriate protective measures such as protective gloves, goggles and protective clothing should be used when handling the compound. At the same time, attention should be paid to taking appropriate ventilation measures to avoid inhaling its dust or steam. Keep away from fire and oxidant during storage. If exposed or inhaled, seek medical attention immediately.

Last Update：2024-04-09 21:11:58