2-氯-5-溴-4-甲基嘧啶

2-氯-5-溴-4-甲基嘧啶 - Names and Identifiers

Name	5-Bromo-2-chloro-4-methylpyrimidine
Synonyms	5-Bromo-2-chloro-4-methylpyrimidine Pyrimidine, 5-bromo-2-chloro-4-methyl-
CAS	633328-95-7

2-氯-5-溴-4-甲基嘧啶 - Physico-chemical Properties

Molecular Formula	C5H4BrClN2
Molar Mass	207.458
Density	1.724±0.06 g/cm3(Predicted)
Boling Point	281.5±20.0 °C(Predicted)
pKa	-2.35±0.29(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-氯-5-溴-4-甲基嘧啶 - Upstream Downstream Industry

Raw Materials

2-Amino-4-methyl-5-bromopyrimidine
Methylmagnesium Bromide
5-Bromo-2,4-dichloropyrimidine

2-氯-5-溴-4-甲基嘧啶 - Introduction

It is an organic compound with the chemical formula C6H5BrClN2 and a molecular weight of 191.48g/mol.

Nature:
is a solid with a white to light yellow crystalline form. It is substantially insoluble in water at normal temperature, but soluble in organic solvents such as ethers and alcohols. It is moderately toxic.

Use:
It is often used as an intermediate in organic synthesis. It can be used to synthesize drugs, pesticides and other organic compounds.

Method:
A commonly used preparation method is by reacting 2-chloro-5-bromo-4-methylpyridine with nitrate in the presence of sulfuric acid. The specific steps include first obtaining 2-chloro-5-bromo-4-methylpyridine, then reacting with nitrate, and finally obtaining the target product by crystallization and purification.

Safety Information:
is a potential organic poison. Contact should avoid inhalation of its dust, avoid skin contact and ingestion. Personal protective equipment such as protective gloves, protective glasses and protective masks should be worn during use. In case of accidental contact, rinse immediately with plenty of water and seek medical help if necessary.

Last Update：2024-04-09 15:18:03