2-氯-5-甲基嘧啶
2-Chloro-5-methylpyrimidine
CAS: 22536-61-4
Molecular Formula: C5H5ClN2
2-氯-5-甲基嘧啶 - Names and Identifiers
| Name | 2-Chloro-5-methylpyrimidine |
| Synonyms | 2-Chlor5-Methyl pyrimidine 2-Chloro-5-methylpyrimidine 2-Chloro-5-methyl-1,3-diazine Pyrimidine, 2-chloro-5-methyl- Pyrimidine, 2-chloro-5-methyl- (8CI,9CI) |
| CAS | 22536-61-4 |
| EINECS | 807-915-1 |
| InChI | InChI=1/C5H5ClN2/c1-4-2-7-5(6)8-3-4/h2-3H,1H3 |
2-氯-5-甲基嘧啶 - Physico-chemical Properties
| Molecular Formula | C5H5ClN2 |
| Molar Mass | 128.56 |
| Density | 1.234±0.06 g/cm3(Predicted) |
| Melting Point | 89-92℃ |
| Boling Point | 239.2±9.0 °C(Predicted) |
| Flash Point | 121.5°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.0628mmHg at 25°C |
| Appearance | Solid |
| pKa | -1.03±0.22(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.529 |
2-氯-5-甲基嘧啶 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29335990 |
2-氯-5-甲基嘧啶 - Introduction
It is an organic compound with the chemical formula C5H5ClN2. The following is a description of its nature, use, preparation and safety information:
Nature:
It is a colorless to yellowish liquid with a special smell. It has a lower boiling point and melting point at room temperature. It is soluble in organic solvents such as diethyl ether, acetone and dichloromethane.
Use:
It is an important organic intermediate, which can be widely used in the synthesis of drugs and pesticides. It is used as an intermediate in the synthesis of a variety of drugs such as antiviral drugs and antitumor drugs. In addition, it can also be used to prepare other organic compounds, such as dyes and coordination compounds.
Method:
The preparation method of calcium can be obtained by reacting 2-methyl pyrimidine with thionyl chloride. The specific reaction conditions can be adjusted according to the experimental requirements, but the common conditions are carried out under inert atmosphere, room temperature or heating.
Safety Information:
It has low toxicity under General use conditions, but appropriate protective measures are still required. During operation, contact with skin, eyes and inhalation of vapors should be avoided, and protective glasses and gloves should be worn if necessary. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help. At the same time, avoid mixing it with strong oxidants and strong acids to avoid fire or explosion. Storage should be placed in a dry, cool, well-ventilated place, away from fire and combustibles.
Nature:
It is a colorless to yellowish liquid with a special smell. It has a lower boiling point and melting point at room temperature. It is soluble in organic solvents such as diethyl ether, acetone and dichloromethane.
Use:
It is an important organic intermediate, which can be widely used in the synthesis of drugs and pesticides. It is used as an intermediate in the synthesis of a variety of drugs such as antiviral drugs and antitumor drugs. In addition, it can also be used to prepare other organic compounds, such as dyes and coordination compounds.
Method:
The preparation method of calcium can be obtained by reacting 2-methyl pyrimidine with thionyl chloride. The specific reaction conditions can be adjusted according to the experimental requirements, but the common conditions are carried out under inert atmosphere, room temperature or heating.
Safety Information:
It has low toxicity under General use conditions, but appropriate protective measures are still required. During operation, contact with skin, eyes and inhalation of vapors should be avoided, and protective glasses and gloves should be worn if necessary. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help. At the same time, avoid mixing it with strong oxidants and strong acids to avoid fire or explosion. Storage should be placed in a dry, cool, well-ventilated place, away from fire and combustibles.
Last Update：2024-04-09 21:11:58
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CAS: 22536-61-4
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View History
2-氯-5-甲基嘧啶
CERIUM(IV) FLUORIDE ANHYDROUS
氢化双酚(HBPA)
Cyclopropanecarboxaldehyde, 1-[(1,1-dimethylethyl)thio]- (9CI)
(2S)-2-AMINO-3-(2-FLUORO-4-METHYLPHENYL)PROPANOIC ACID HYDROCHLORIDE
Benzoic acid, 4-[(2-formylphenoxy)methyl]-
7-NAPHTHLENE DISULFONIC ACID
3-Amino-cyclohexanol(mixture of cis-and trans-)
5-(2-硫氰酸乙酰基)噻吩-2-甲酰胺
2-溴-3-氨基-5-氯吡啶
CERIUM(IV) FLUORIDE ANHYDROUS
氢化双酚(HBPA)
Cyclopropanecarboxaldehyde, 1-[(1,1-dimethylethyl)thio]- (9CI)
(2S)-2-AMINO-3-(2-FLUORO-4-METHYLPHENYL)PROPANOIC ACID HYDROCHLORIDE
Benzoic acid, 4-[(2-formylphenoxy)methyl]-
7-NAPHTHLENE DISULFONIC ACID
3-Amino-cyclohexanol(mixture of cis-and trans-)
5-(2-硫氰酸乙酰基)噻吩-2-甲酰胺
2-溴-3-氨基-5-氯吡啶