2-氯代异丁酰氯
2-CHLOROISOBUTYRYL CHLORIDE
CAS: 13222-26-9
Molecular Formula: C4H6Cl2O
2-氯代异丁酰氯 - Names and Identifiers
2-氯代异丁酰氯 - Physico-chemical Properties
| Molecular Formula | C4H6Cl2O |
| Molar Mass | 141 |
| Density | 1.1802 |
| Boling Point | 189.51°C (rough estimate) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.4369 (estimate) |
2-氯代异丁酰氯 - Introduction
2-Chloroisobutyryl chloride, also known as 2-chloro-2-methylbutyryl chloride, has the chemical formula ClC(CH3)2COCl. Its nature, use, formulation and safety information are described below.
Nature:
2-Chloroisobutyryl chloride is a colorless to pale yellow liquid with a pungent odor. It is an acid chloride compound with high reactivity.
Use:
2-chloroisobutyryl chloride is commonly used as a reagent for organic synthesis, such as for drug synthesis, pesticide synthesis, etc. It can be used to prepare compounds such as amides, esters, ketones and acid chlorides.
Preparation Method:
The preparation of 2-chloroisobutyryl chloride can be obtained by reacting 2-isobutyric acid with thionyl chloride. First, 2-isobutyric acid and thionyl chloride are mixed at a low temperature to produce 2-chloroisobutyryl sulfoxide. The product is then reacted with hydrochloric acid to give the final product 2-chloroisobutyryl chloride.
Safety Information:
2-Chloroisobutyryl chloride has a pungent odor and is irritating to the eyes, skin and respiratory tract. During use, attention should be paid to protective measures to avoid inhalation or contact with skin and eyes. In case of accidental contact, please wash with water in time and seek medical help. In addition, 2-chloroisobutyryl chloride should be stored separately from oxidants and strong bases during storage and transportation to avoid dangerous accidents.
Nature:
2-Chloroisobutyryl chloride is a colorless to pale yellow liquid with a pungent odor. It is an acid chloride compound with high reactivity.
Use:
2-chloroisobutyryl chloride is commonly used as a reagent for organic synthesis, such as for drug synthesis, pesticide synthesis, etc. It can be used to prepare compounds such as amides, esters, ketones and acid chlorides.
Preparation Method:
The preparation of 2-chloroisobutyryl chloride can be obtained by reacting 2-isobutyric acid with thionyl chloride. First, 2-isobutyric acid and thionyl chloride are mixed at a low temperature to produce 2-chloroisobutyryl sulfoxide. The product is then reacted with hydrochloric acid to give the final product 2-chloroisobutyryl chloride.
Safety Information:
2-Chloroisobutyryl chloride has a pungent odor and is irritating to the eyes, skin and respiratory tract. During use, attention should be paid to protective measures to avoid inhalation or contact with skin and eyes. In case of accidental contact, please wash with water in time and seek medical help. In addition, 2-chloroisobutyryl chloride should be stored separately from oxidants and strong bases during storage and transportation to avoid dangerous accidents.
Last Update：2024-04-09 21:01:54
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View History
2-氯代异丁酰氯
CATACXIUM A
A-TOLUENESULFONYL FLUORIDE
苯并[D]噻唑-2-甲酸乙酯
TRANS-1,4-CYCLOHEXYLENE DIISOCYANATE
牛脂基二甲基叔胺
5-(2-Cyanophenyl)nicotinonitrile
crystal violet 6b
[(3,5-二甲基-1-丙基-1H-吡唑-4-基)甲基]胺盐酸盐
三(乙烯醇) 单-11-十一烷基硫醇
CATACXIUM A
A-TOLUENESULFONYL FLUORIDE
苯并[D]噻唑-2-甲酸乙酯
TRANS-1,4-CYCLOHEXYLENE DIISOCYANATE
牛脂基二甲基叔胺
5-(2-Cyanophenyl)nicotinonitrile
crystal violet 6b
[(3,5-二甲基-1-丙基-1H-吡唑-4-基)甲基]胺盐酸盐
三(乙烯醇) 单-11-十一烷基硫醇