2-氯烟酰胺
2-Chloronicotinamide
CAS: 10366-35-5
Molecular Formula: C6H5ClN2O
2-氯烟酰胺 - Names and Identifiers
| Name | 2-Chloronicotinamide |
| Synonyms | RARECHEM AH CK 0070 TIMTEC-BB SBB004012 2-Chloronicotinamide 2-CHLORONICOTINAMIDE 2-CHLORONICOTINAMIDE CNAM 2-Chloropyridine-3-carboxamide 2-CHLOROPYRIDINE-3-CARBOXAMIDE 2-Chloro-N,N'-dimethylnicotinamide 2-CHLORO-PYRIDIN-3-CARBOXYLIC ACID AMIDE 2-CHLORO-NICOTINAMIDE, 2-CHLORO-PYRIDINE-3-CARBOXYLIC ACID AMIDE |
| CAS | 10366-35-5 |
| EINECS | 233-808-9 |
| InChI | InChI=1/C6H5ClN2O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,8,10) |
2-氯烟酰胺 - Physico-chemical Properties
| Molecular Formula | C6H5ClN2O |
| Molar Mass | 156.57 |
| Density | 1.4411 (rough estimate) |
| Melting Point | 164-167°C(lit.) |
| Boling Point | 313.7±27.0 °C(Predicted) |
| Flash Point | 143.5°C |
| Vapor Presure | 0.000487mmHg at 25°C |
| Appearance | Light brown fine crystalline powder |
| Color | Beige |
| BRN | 119026 |
| pKa | 14.19±0.50(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.5400 (estimate) |
| MDL | MFCD00006237 |
2-氯烟酰胺 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
2-氯烟酰胺 - Introduction
2-Chloronicotinamide is an organic compound with the chemical formula ClC6H3(CO)NH2. Its nature is as follows:
Nature:
1. Appearance: 2-chloronicotinic acid amide is colorless to light yellow crystal.
2. Melting point: about 158-161°C.
3. Solubility: Soluble in most organic solvents, such as alcohols and ketones, insoluble in water.
Use:
1. 2-Chloronicotinic acid amide can be used as raw materials and intermediates in organic synthesis.
2. It is widely used in the synthesis of drugs, dyes, coatings and pesticides and other chemicals.
3. 2-chloronicotinamide can also be used as a rubber processing aid and flame retardant for polyamide fibers.
Preparation Method:
2-Chloronicotinic acid amide can be prepared by reacting 2-chloronicotinic acid with ammonia. A specific synthesis method involves reacting 2-chloronicotinic acid with ammonia under alkaline conditions to produce 2-chloronicotinamide.
Safety Information:
1. 2-Chloronicotinamide should be avoided by inhalation, contact with skin, or ingestion. Appropriate operational measures should be taken, such as wearing protective gloves, wearing suitable protective clothing, etc.
2. When using or storing 2-chloronicotinic acid amide, you should pay attention to avoid fire sources and maintain a well-ventilated working environment.
3. If you come into contact with 2-chloronicotinamide, immediately flush the affected area with plenty of water and seek medical help.
4. 2-Chloronicotinamide is hazardous and should be stored properly and kept away from children and animals.
Nature:
1. Appearance: 2-chloronicotinic acid amide is colorless to light yellow crystal.
2. Melting point: about 158-161°C.
3. Solubility: Soluble in most organic solvents, such as alcohols and ketones, insoluble in water.
Use:
1. 2-Chloronicotinic acid amide can be used as raw materials and intermediates in organic synthesis.
2. It is widely used in the synthesis of drugs, dyes, coatings and pesticides and other chemicals.
3. 2-chloronicotinamide can also be used as a rubber processing aid and flame retardant for polyamide fibers.
Preparation Method:
2-Chloronicotinic acid amide can be prepared by reacting 2-chloronicotinic acid with ammonia. A specific synthesis method involves reacting 2-chloronicotinic acid with ammonia under alkaline conditions to produce 2-chloronicotinamide.
Safety Information:
1. 2-Chloronicotinamide should be avoided by inhalation, contact with skin, or ingestion. Appropriate operational measures should be taken, such as wearing protective gloves, wearing suitable protective clothing, etc.
2. When using or storing 2-chloronicotinic acid amide, you should pay attention to avoid fire sources and maintain a well-ventilated working environment.
3. If you come into contact with 2-chloronicotinamide, immediately flush the affected area with plenty of water and seek medical help.
4. 2-Chloronicotinamide is hazardous and should be stored properly and kept away from children and animals.
Last Update：2024-04-09 15:17:50
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