2-溴-3-醛基吡啶
2-Bromo-3-formylpyridine
CAS: 128071-75-0
Molecular Formula: C6H4BrNO
2-溴-3-醛基吡啶 - Names and Identifiers
| Name | 2-Bromo-3-formylpyridine |
| Synonyms | 2-Bromonicotinaldehyde 2-BROMONICOTINALDEHYDE 2-BROMO-3-FORMYLPYRIDINE 2-Bromo-3-formylpyridine 2-Bromopyridine-3-carbaldehyde 2-BROMO-PYRIDINE-3-CARBALDEHYDE 2-Bromo-Pyridine-3-Carbaldehyde 2-BROMOPYRIDINE-3-CARBOXALDEHYDE 2-BROMO-3-PYRIDINECARBOXALDEHYDE 2-Bromopyridine-3-Carboxaldehyde 2-Bromo-3-Pyridinecarboxaldehyde 2-Bromopyridine-3-carboxaldehyde, 2-Bromo-3-formylpyridine |
| CAS | 128071-75-0 |
| InChI | InChI=1/C6H4BrNO/c7-6-5(4-9)2-1-3-8-6/h1-4H |
| InChIKey | GNFWMEFWZWXLIN-UHFFFAOYSA-N |
2-溴-3-醛基吡啶 - Physico-chemical Properties
| Molecular Formula | C6H4BrNO |
| Molar Mass | 186.01 |
| Density | 1.683±0.06 g/cm3(Predicted) |
| Melting Point | 73 °C |
| Boling Point | 100 °C / 3mmHg |
| Flash Point | 115.7°C |
| Vapor Presure | 0.00802mmHg at 25°C |
| Appearance | White to yellow to brown powder |
| Color | White to Orange to Green |
| pKa | -1.01±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.619 |
| MDL | MFCD04966945 |
| Physical and Chemical Properties | WGK Germany:3 |
2-溴-3-醛基吡啶 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
2-溴-3-醛基吡啶 - Introduction
2-Bromo-3-pyridinecarboxaldehyde is an organic compound whose chemical formula is C7H6BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Bromo-3-pyridinecarboxaldehyde is a colorless to pale yellow liquid with a characteristic odor of pyridine and aldehyde. It is soluble in most organic solvents at room temperature and insoluble in water. It is a highly reactive compound that can undergo various organic reactions under certain conditions.
Use:
2-Bromo-3-pyridinecarboxaldehyde has a wide range of applications in organic synthesis. It is often used as an intermediate in organic synthesis for the synthesis of other organic compounds, such as drugs, pesticides and dyes. It can participate in specific reactions, such as boric acid etherification reaction, aldol condensation reaction, etc.
Preparation Method:
2-Bromo-3-pyridinecarboxaldehyde can be prepared by reacting 3-pyridinecarboxaldehyde with hydrogen bromide. Hydrogen bromide was first introduced into a solution of 3-pyridinecarboxaldehyde in methanol through a gas wash bottle and the reaction mixture was then heated. After completion of the reaction, the target product is obtained by a method such as steam distillation or extraction.
Safety Information:
2-Bromo-3-pyridinecarboxaldehyde is an organic compound that requires appropriate safety precautions when used or handled. It can be irritating and corrosive to the skin, eyes and respiratory tract. When in use, should ensure good ventilation, and wear protective gloves, glasses and masks and other protective equipment. Avoid inhalation, ingestion or contact with skin. After accidental contact, rinse immediately with plenty of water and seek medical help. During storage, it should be kept away from combustibles and oxidants and stored in a cool and dry place.
Nature:
2-Bromo-3-pyridinecarboxaldehyde is a colorless to pale yellow liquid with a characteristic odor of pyridine and aldehyde. It is soluble in most organic solvents at room temperature and insoluble in water. It is a highly reactive compound that can undergo various organic reactions under certain conditions.
Use:
2-Bromo-3-pyridinecarboxaldehyde has a wide range of applications in organic synthesis. It is often used as an intermediate in organic synthesis for the synthesis of other organic compounds, such as drugs, pesticides and dyes. It can participate in specific reactions, such as boric acid etherification reaction, aldol condensation reaction, etc.
Preparation Method:
2-Bromo-3-pyridinecarboxaldehyde can be prepared by reacting 3-pyridinecarboxaldehyde with hydrogen bromide. Hydrogen bromide was first introduced into a solution of 3-pyridinecarboxaldehyde in methanol through a gas wash bottle and the reaction mixture was then heated. After completion of the reaction, the target product is obtained by a method such as steam distillation or extraction.
Safety Information:
2-Bromo-3-pyridinecarboxaldehyde is an organic compound that requires appropriate safety precautions when used or handled. It can be irritating and corrosive to the skin, eyes and respiratory tract. When in use, should ensure good ventilation, and wear protective gloves, glasses and masks and other protective equipment. Avoid inhalation, ingestion or contact with skin. After accidental contact, rinse immediately with plenty of water and seek medical help. During storage, it should be kept away from combustibles and oxidants and stored in a cool and dry place.
Last Update：2024-04-09 15:17:51
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