2-碘苯甲酸叔丁酯
tert-Butyl 2-iodobenzoate
CAS: 110349-26-3
Molecular Formula: C11H13IO2
2-碘苯甲酸叔丁酯 - Names and Identifiers
| Name | tert-Butyl 2-iodobenzoate |
| Synonyms | t-Butyl2-iodobenzoate Telmisartan EP Impurity 2 tert-Butyl 2-iodobenzoate Benzoic acid, 2-iodo-, 1,1-dimethylethyl ester |
| CAS | 110349-26-3 |
2-碘苯甲酸叔丁酯 - Physico-chemical Properties
| Molecular Formula | C11H13IO2 |
| Molar Mass | 304.12 |
| Density | 1.528±0.06 g/cm3(Predicted) |
| Boling Point | 142 °C(Press: 1 Torr) |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD11044440 |
2-碘苯甲酸叔丁酯 - Introduction
tert-Butyl 2-iodobenzoate is an organic compound with the chemical formula C11H13IO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder or solid;
-Solubility: Soluble in organic solvents, such as ethyl acetate and dimethyl sulfite;
-Melting point: about 58-60 ℃.
Use:
tert-Butyl 2-iodobenzoate is commonly used as a reagent in organic synthesis. It is one of the important intermediates in the synthesis of other compounds. For example, it can be used to synthesize p-toluenesulfonate acetate, or it can be prepared as tert-butyl 2-benzoate by reduction.
Preparation Method:
The common preparation method is to add sodium iodide or cuprous iodide to tert-butyl benzoate for iodination reaction. The specific operation can refer to the organic chemical synthesis manual or related literature.
Safety Information:
tert-Butyl 2-iodobenzoate needs to pay attention to the following safety precautions when handling:
-contact: avoid skin contact, can use protective gloves and clothing;
-Inhalation: Avoid inhaling dust, and the operation should be carried out in a well-ventilated place;
-Ingestion: Do not eat or drink, keep away from children and pets.
In addition, the use of chemicals must follow the relevant regulations and safety procedures, the specific operation should be carried out according to the laboratory safety requirements and chemical safety data sheets. Be sure to use and store chemicals in the right environment.
Nature:
-Appearance: White crystalline powder or solid;
-Solubility: Soluble in organic solvents, such as ethyl acetate and dimethyl sulfite;
-Melting point: about 58-60 ℃.
Use:
tert-Butyl 2-iodobenzoate is commonly used as a reagent in organic synthesis. It is one of the important intermediates in the synthesis of other compounds. For example, it can be used to synthesize p-toluenesulfonate acetate, or it can be prepared as tert-butyl 2-benzoate by reduction.
Preparation Method:
The common preparation method is to add sodium iodide or cuprous iodide to tert-butyl benzoate for iodination reaction. The specific operation can refer to the organic chemical synthesis manual or related literature.
Safety Information:
tert-Butyl 2-iodobenzoate needs to pay attention to the following safety precautions when handling:
-contact: avoid skin contact, can use protective gloves and clothing;
-Inhalation: Avoid inhaling dust, and the operation should be carried out in a well-ventilated place;
-Ingestion: Do not eat or drink, keep away from children and pets.
In addition, the use of chemicals must follow the relevant regulations and safety procedures, the specific operation should be carried out according to the laboratory safety requirements and chemical safety data sheets. Be sure to use and store chemicals in the right environment.
Last Update：2024-04-10 22:29:15
