2-芳基-1,3-二氢苯并咪唑 - Names and Identifiers
2-芳基-1,3-二氢苯并咪唑 - Physico-chemical Properties
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2-芳基-1,3-二氢苯并咪唑 - Introduction
2-aryl-1, 3-didrobenzimidazole is a compound containing a benzimidazole structure with the chemical formula C9H8N2. Its aryl group can be various aromatic substituents, such as benzene ring, thiophene, imidazole, pyrrole, etc. This compound has some special properties and uses.
Nature:
2-aryl-1,3-dihydrobenzimidazole is a white to yellowish crystalline solid. It is soluble in a variety of organic solvents at room temperature, such as alcohols, ethers and chlorinated hydrocarbons. It has strong stability to air and can be stored for a long time under normal storage conditions.
Use:
2-aryl-1,3-dihydrobenzimidazole has a wide range of uses in the pharmaceutical field. It is an important pharmaceutical intermediate, which can be used to synthesize a variety of bioactive compounds, such as anti-tumor drugs, antibacterial drugs, antiviral drugs and so on. In addition, it can also be used as a catalyst and an oxidant for organic synthesis reactions.
Preparation Method:
2-aryl-1,3-dihydrobenzimidazole has various preparation methods, including the following common ones: 1) reaction of aromatic amine with enacetone; 2) reaction of aromatic amine with aldehyde; 3) coupling reaction of two aromatic amine molecules; 4) condensation reaction of imidazole with aryl bromide, etc.
Safety Information:
2-aryl-1,3-dihydrobenzimidazole is a relatively safe compound, but the following matters still need to be paid attention:
1) Wear appropriate protective gloves and eye protection equipment, and avoid direct contact with skin or inhalation of dust during operation.
2) When using or preparing, it should be operated in a well-ventilated laboratory environment to avoid excessive vapor concentration.
3) storage should be sealed, and placed in a cool, dry place, away from the fire and oxidant.
4) Follow the correct operating methods and waste disposal regulations to ensure safety and environmental protection.
Last Update：2024-04-09 20:52:54