200197-04-2
4-carbamoylphenylcarbamic acid 2,5-dioxyopyrrolidin-1-yl ester
CAS: 200197-04-2
Molecular Formula: C12H11N3O5
200197-04-2 - Names and Identifiers
| Name | 4-carbamoylphenylcarbamic acid 2,5-dioxyopyrrolidin-1-yl ester |
| Synonyms | 4-carbamoylphenylcarbamic acid 2,5-dioxyopyrrolidin-1-yl ester |
| CAS | 200197-04-2 |
200197-04-2 - Physico-chemical Properties
| Molecular Formula | C12H11N3O5 |
| Molar Mass | 277.23 |
200197-04-2 - Introduction
4-carbamoylphenylcarbamic acid 2, also known as 4-carbamoylphenylcarbamic acid, ester, is a compound with the following properties:
1. Appearance: colorless or white crystalline or powdery solid;
2. molecular formula: C13H16N2O4;
3. Molecular weight: 276.28g/mol;
4. Melting point: about 120-122 degrees Celsius.
The main uses of this compound include:
1. Pharmaceutical field: As a nucleotide reverse transcriptase inhibitor, it can be used to treat hepatitis B virus infection;
2. biochemical research: can be used for the synthesis of DNA and RNA nucleic acid chain terminator.
The method of preparing the compound generally includes the following steps:
1. first, reacting 4-carbamanilide with formyl chloride to obtain 4-carbamoylaniline;
2. Then, 4-carbamoylaniline is reacted with succinimidyl ester to generate 4-carbamoylphenylcarbamic acid 2, methyl ester.
For safety information, this compound may be toxic and should be used in strict compliance with laboratory practices and wearing personal protective equipment to ensure safety. At the same time, during use, avoid contact with skin and eyes, and avoid inhaling or ingesting the compound. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
Please note that when using or handling any chemical, you should carefully read and follow the safety data sheet and relevant operating instructions.
1. Appearance: colorless or white crystalline or powdery solid;
2. molecular formula: C13H16N2O4;
3. Molecular weight: 276.28g/mol;
4. Melting point: about 120-122 degrees Celsius.
The main uses of this compound include:
1. Pharmaceutical field: As a nucleotide reverse transcriptase inhibitor, it can be used to treat hepatitis B virus infection;
2. biochemical research: can be used for the synthesis of DNA and RNA nucleic acid chain terminator.
The method of preparing the compound generally includes the following steps:
1. first, reacting 4-carbamanilide with formyl chloride to obtain 4-carbamoylaniline;
2. Then, 4-carbamoylaniline is reacted with succinimidyl ester to generate 4-carbamoylphenylcarbamic acid 2, methyl ester.
For safety information, this compound may be toxic and should be used in strict compliance with laboratory practices and wearing personal protective equipment to ensure safety. At the same time, during use, avoid contact with skin and eyes, and avoid inhaling or ingesting the compound. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
Please note that when using or handling any chemical, you should carefully read and follow the safety data sheet and relevant operating instructions.
Last Update：2024-04-09 21:11:58
