Name | PAT-1251 |
Synonyms | PAT-1251 2007885-39-2 Methanone, [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl][(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]-, rel- |
CAS | 2007885-39-2 |
Molecular Formula | C18H17F4N3O3 |
Molar Mass | 399.34 |
Density | 1.48±0.1 g/cm3(Predicted) |
Boling Point | 540.7±50.0 °C(Predicted) |
pKa | 13.23±0.40(Predicted) |
Storage Condition | 2-8℃ |
Use | PAT-1251 is a potent, selective, orally available inhibitor of lysyl oxidase-like protein 2 (LOXL2), the IC50 values for hLOXL2 and hLOXL3 were 0.71 and 1.17 μm, respectively, |