201286-99-9
6-Hydroxy-3-methylindazole
CAS: 201286-99-9
Molecular Formula: C8H8N2O
201286-99-9 - Names and Identifiers
| Name | 6-Hydroxy-3-methylindazole |
| Synonyms | 3-Methylindazol-6-ol 3-methyl-1H-indazol-6-ol 6-Hydroxy-3-methylindazole 1H-Indazol-6-ol, 3-methyl- 1H-indazol-6-ol, 3-methyl- 3-methyl-1,2-dihydroindazol-6-one |
| CAS | 201286-99-9 |
| InChI | InChI=1/C8H8N2O/c1-5-7-3-2-6(11)4-8(7)10-9-5/h2-4,11H,1H3,(H,9,10) |
201286-99-9 - Physico-chemical Properties
| Molecular Formula | C8H8N2O |
| Molar Mass | 148.16 |
| Density | 1.349±0.06 g/cm3(Predicted) |
| Boling Point | 366.0±22.0 °C(Predicted) |
| Flash Point | 175.152°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 9.26±0.40(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.719 |
201286-99-9 - Introduction
6-Hydroxy-3-methylindazole (3-methyll-6-hydroxyindazole) is an organic compound with the chemical formula C9H8N2O and a molecular weight of 160.17g/mol. The following is a description of the nature, use, preparation and safety information of 6-Hydroxy-3-methylindazole:
Nature:
-Appearance: 6-Hydroxy-3-methylindazole is a white to light yellow solid.
-Solubility: It has low solubility in water and better solubility in organic solvents (such as ethanol and dimethyl sulfoxide).
-Melting point: The melting point of 6-hydroxyy-3-methylindazole is about 212-216°C.
-Stability: It is relatively stable at room temperature, but may decompose under light.
Use:
-Chemical research: 6-Hydroxy-3-methylindazole is an important starting material and intermediate, often used in the synthesis of other indazole compounds (such as fluorescent dyes, pharmaceutical compounds).
-Fluorescent probe: Due to its unique fluorescent properties, 6-hydroxyy-3-methylindazole is also used as a fluorescent probe, which can be used in fields such as biological analysis and microscopy.
Method:
- 6-Hydroxy-3-methylindazole can be prepared by a variety of synthetic routes. One of the commonly used methods is to react p-nitrobenzoic acid with acetic anhydride, and then go through the steps of reduction and cyclization.
Safety Information:
-The specific hazard information and safety precautions of 6-Hydroxy-3-methylindazole shall be determined according to the specific situation and the environment in which it is used. Therefore, users are required to strictly follow the safety data sheets and operating instructions provided by the chemical supplier.
-Avoid contact with strong acids, alkalis and inflammables during operation and storage.
-Good personal protective measures should be taken during operation, such as wearing chemical protective glasses, protective gloves and laboratory clothing.
Nature:
-Appearance: 6-Hydroxy-3-methylindazole is a white to light yellow solid.
-Solubility: It has low solubility in water and better solubility in organic solvents (such as ethanol and dimethyl sulfoxide).
-Melting point: The melting point of 6-hydroxyy-3-methylindazole is about 212-216°C.
-Stability: It is relatively stable at room temperature, but may decompose under light.
Use:
-Chemical research: 6-Hydroxy-3-methylindazole is an important starting material and intermediate, often used in the synthesis of other indazole compounds (such as fluorescent dyes, pharmaceutical compounds).
-Fluorescent probe: Due to its unique fluorescent properties, 6-hydroxyy-3-methylindazole is also used as a fluorescent probe, which can be used in fields such as biological analysis and microscopy.
Method:
- 6-Hydroxy-3-methylindazole can be prepared by a variety of synthetic routes. One of the commonly used methods is to react p-nitrobenzoic acid with acetic anhydride, and then go through the steps of reduction and cyclization.
Safety Information:
-The specific hazard information and safety precautions of 6-Hydroxy-3-methylindazole shall be determined according to the specific situation and the environment in which it is used. Therefore, users are required to strictly follow the safety data sheets and operating instructions provided by the chemical supplier.
-Avoid contact with strong acids, alkalis and inflammables during operation and storage.
-Good personal protective measures should be taken during operation, such as wearing chemical protective glasses, protective gloves and laboratory clothing.
Last Update：2024-04-09 21:04:16
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CAS: 201286-99-9
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Mobile: 18021002903
QQ: 3008007409
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CAS: 201286-99-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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