2023788-32-9
2-Azetidineacetic acid, 1-[[(2-methylphenyl)amino]carbonyl]-4-oxo-
CAS: 2023788-32-9
Molecular Formula: C13H14N2O4
2023788-32-9 - Names and Identifiers
| Name | 2-Azetidineacetic acid, 1-[[(2-methylphenyl)amino]carbonyl]-4-oxo- |
| Synonyms | Integrin modulator 1 2-Azetidineacetic acid, 1-[[(2-methylphenyl)amino]carbonyl]-4-oxo- |
| CAS | 2023788-32-9 |
2023788-32-9 - Physico-chemical Properties
| Molecular Formula | C13H14N2O4 |
| Molar Mass | 262.26 |
| In vitro study | Integrin modulator 1 (2-10 μg/mL; 30 min) significantly increases Jurkat E6.1 cell adhesion. Integrin modulator 1 (1-100 nM; 1 h) strongly and significantly increases ERK1/2 phosphorylation in Jurkat E6.1 cells. Integrin modulator 1 (1 nM-10 μM; 30 min) significantly increases the binding of HUTS-21 antibody to Jurkat E6.1 cells in a concentration-dependent manner. |
2023788-32-9 - Reference Information
| biological activity | Integrin modulator 1 is an effective and selective α4β1 integrin agonist with an IC50 value of 9.8 nM. Integrin modulator 1 increased α4β1 integrin-mediated cell adhesion with an EC50 value of 12.9 nM. |
| target | α4β1 9.8 nM (IC 50 ) |
| in vitro study | Integrin modulator 1 (2-10 μg/mL; 30 min) significantly increases Jurkat E6.1 cell adhesion. Integrin modulator 1 (1-100 nM; 1 h) strongly and significantly increases ERK1/2 phosphorylation in Jurkat E6.1 cells. Integrin modulator 1 (1 nM-10 μM; 30 min) significantly increases the binding of HUTS-21 antibody to Jurkat E6.1 cells in a concentration-dependent manner. |
Last Update：2024-04-09 15:16:42
