205526-40-5 - Names and Identifiers
205526-40-5 - Physico-chemical Properties
Molecular Formula | C26H23NO4
|
Molar Mass | 413.47 |
Density | 1.298±0.06 g/cm3(Predicted) |
Boling Point | 656.8±43.0 °C(Predicted) |
pKa | 3.80±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
205526-40-5 - Risk and Safety
205526-40-5 - Introduction
1H-Indene-2-aceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-, (aR)-is an amino acid derivative. Its properties include:
-Molecular formula: C25H23NO4
-Molecular weight: 401.46g/mol
-Appearance: White solid powder
-Melting Point: 178-180 ℃
1H-Indene-2-aceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-, (aR)-commonly used in drug synthesis and antitumor drug research. It can be used as an active unit in medicinal chemistry for the synthesis of peptides and proteins. By introducing the Fmoc-protecting group, the reactivity of the amino acid can be effectively controlled during the synthesis.
The method of preparing 1H-Indene-2-aceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-, (aR)-is complicated, it is usually done in an organic synthesis laboratory. A common synthetic method is to react D-2-indanylglycine with Fmoc-carbamene (Fmoc-Cl) to form the target compound. The specific steps and conditions of the synthesis will vary, and the specific operation needs to refer to the relevant synthesis literature.
Regarding the safety information of 1H-Indene-2-aceticacid, a-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-, (aR)-, its toxicity and danger are relatively low. However, when performing laboratory operations, care should be taken to follow relevant safety procedures and protective measures. This includes wearing suitable personal protective equipment (such as laboratory gloves, goggles and laboratory coats), operating in well-ventilated conditions, and avoiding contact with skin, eyes and inhalation of gas or dust. When dealing with this substance, it is best to take appropriate waste treatment measures to avoid pollution to the environment. The relevant safety data sheet and operating instructions for the compound should be read carefully before use.
Last Update:2024-04-09 21:32:39