Name | 6H05 TFA |
Synonyms | 6H05 TFA K-RAS INHIBITOR K-RAS INHIBITOR 6H05 TFA |
CAS | 2061344-88-3 |
Molecular Formula | C22H31ClF3N3O4S3 |
Molar Mass | 590.13 |
In vitro study | 6H05 gives the greatest degree of modification, allosteric modification of the highly homologous protein H-Ras of the oncogenic G12C mutant without affecting the wild-type K-Ras. In addition, 6H05 can be used as an intermediate in the synthesis of other oncogenic K-Ras(G12C) inhibitors. |
biological activity | 6H05 is a selective, allosteric inhibitor of oncogenic K-Ras(G12C). |
Target | Value |