209959-33-1

209959-33-1 - Names and Identifiers

Name	di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate
Synonyms	N,N-bis-Boc-2-aMino-5-broMopyriMidine 2-(N,N-BisBOC-Amino)-5-bromopyrimidine 2-Amino-5-bromopyrimidine, 2,2-Bis-BOC protected 2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE (5-Bromopyrimidin-2-yl)bis(tert-butoxycarbonyl)amine di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate Di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate tert-butyl N-(5-broMopyriMidin-2-yl)-N-[(tert-butoxy)carbonyl]carbaMate Imidodicarbonicacid2-(5-bromo-2-pyrimidinyl)-1,3-bis(1,1-dimethylethyl)ester Imidodicarbonic acid 2-(5-bromo-2-pyrimidinyl)-1,3-bis(1,1-dimethylethyl) ester
CAS	209959-33-1
InChI	InChI=1/C14H20BrN3O4/c1-13(2,3)21-11(19)18(12(20)22-14(4,5)6)10-16-7-9(15)8-17-10/h7-8H,1-6H3

209959-33-1 - Physico-chemical Properties

Molecular Formula	C14H20BrN3O4
Molar Mass	374.23
Density	1.390
Boling Point	415.2±37.0 °C(Predicted)
Flash Point	204.904°C
Vapor Presure	0mmHg at 25°C
pKa	-2.49±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.544

209959-33-1 - Introduction

di-tert-butyl (5-brobropyrimidin-2-yl) imididicarbonate (OXA) is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate is a white or off-white solid with chemical stability. It is stable at room temperature and can be stored under dry conditions.

Use:
di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate is an important intermediate in organic synthesis. It is often used as a starting material for the construction of pyrimidine compounds in organic synthesis. Specifically, it can be used in the synthesis of pyrimidine drugs, pesticides, dyes and other organic compounds. Due to the importance of its organic synthesis, it is widely used in the pharmaceutical and chemical industries.

Method:
The preparation method of di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate is mainly realized by chemical synthesis. A common method of preparation is the reaction of 5-bromopyrimidine and diphenylphosphazene (DPPA) in the presence of potassium carbonate to yield the corresponding N,N-Boc-5-bromopyrimidine hydrochloride. This hydrochloride is then reacted with hydrogen ammonia solution to give di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate. During the preparation process, attention should be paid to safety and laboratory operation specifications should be followed.

Safety Information:
di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate is relatively safe under correct operating conditions, but it still needs to follow laboratory safety operating regulations. It is an organic compound that is potentially dangerous and may cause irritation and harm to the human body. Therefore, when handling and using the compound, it is necessary to wear appropriate protective equipment, such as gloves and goggles, ensure that the experimental environment is well ventilated, and follow relevant safe handling guidelines.

Last Update：2024-04-09 20:48:19