21392-57-4
5,7-DIMETHOXYFLAVONE
CAS: 21392-57-4
Molecular Formula: C17H14O4
21392-57-4 - Names and Identifiers
21392-57-4 - Physico-chemical Properties
| Molecular Formula | C17H14O4 |
| Molar Mass | 282.29 |
| Density | 1.242±0.06 g/cm3(Predicted) |
| Melting Point | 150-152°C |
| Boling Point | 476.6±45.0 °C(Predicted) |
| Solubility | Insuluble (8.8E-3 g/L) (25 °C) |
| Appearance | White crystal |
| Color | Off-White to Pale Brown |
| Storage Condition | -20°C Freezer |
| MDL | MFCD00016943 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from cockscomb; Jin Fenghua. |
21392-57-4 - Reference Information
| Use | Colene dimethyl ether is a potential therapeutic agent, polymethoxyflavone isolated from kaempferol prevents cataracts by inhibiting matrix metalloproteinase-9 in lens epithelial cells. |
| biological activity | 5,7-Dimethoxyflavone (5,7-DMF) is a cytochrome P450 (CYP) 3As inhibitor, can significantly reduce the expression of CYP3A11 and CYP3A25 in the liver. 5,7-Dimethoxyflavone (5,7-DMF) is also a potent inhibitor of Breast Cancer Resistance Protein (BCRP, ABCG2). 5,7-Dimethoxyflavone (5,7-DMF) is one of the main components of Kaempferia parviflora, which has anti-obesity, anti-inflammatory and anti-tumor effects. |
| Target | Value |
Last Update：2024-04-09 18:58:34
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