Name | 2'-O-Methylguanosine |
Synonyms | 2'-OMe-G 2'-OMe Guanosine 2'-O-Methylguanosine 2'-O-METHYLGUANOSINE 2'-O-Methyl-D-guanosine 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one 2-azanyl-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]-3H-purin-6-one 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one |
CAS | 2140-71-8 |
InChI | InChI=1/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1 |
InChIKey | OVYNGSFVYRPRCG-KQYNXXCUSA-N |
Molecular Formula | C11H15N5O5 |
Molar Mass | 297.27 |
Density | 1.98±0.1 g/cm3(Predicted) |
Melting Point | 227-231°C (dec.) |
Boling Point | 711.7°C at 760 mmHg |
Flash Point | 384.2°C |
Solubility | Aqueous Base (Slightly), DMSO (Slightly), |
Vapor Presure | 2.93E-21mmHg at 25°C |
Appearance | White solid |
Color | White to Off-white |
pKa | 9?+-.0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.829 |
MDL | MFCD00057053 |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S60 - This material and its container must be disposed of as hazardous waste. S36/37 - Wear suitable protective clothing and gloves. |
HS Code | 29349990 |
Biological activity | 2 '-O-Methylguanosine is a modified nucleoside, produced under the action of tRNA guanosine -2'-o-methyltransferase. 2 '-O-Methylguanosine has certain apoptosis-promoting effect. |