214045-85-9

214045-85-9 - Names and Identifiers

Name	6-fluoroisoquinolin-1(2H)-one
Synonyms	6-fluoroisoquinolin-1-ol 6-fluoroisoquinolin-1(2H)-one 6-Fluoroisoquinolin-1(2H)-one 6-fluoro-1(2H)-Isoquinolinone 6-fluoro-2H-isoquinolin-1-one 1(2H)-Isoquinolinone, 6-fluoro- 6-hydroxynaphthalen-2-yl acetate 1(2H)-Isoquinolinone,6-fluoro-(9CI) 6-fluoro-1,2-dihydroisoquinolin-1-one
CAS	214045-85-9
InChI	InChI=1/C9H6FNO/c10-7-1-2-8-6(5-7)3-4-11-9(8)12/h1-5H,(H,11,12)

214045-85-9 - Physico-chemical Properties

Molecular Formula	C9H6FNO
Molar Mass	163.15
Density	1.291±0.06 g/cm3(Predicted)
Boling Point	392.6±42.0 °C(Predicted)
pKa	12.31±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.571

214045-85-9 - Introduction

6-fluoroisoquinolin-1(2H)-one is an organic compound with the chemical formula C9H5FNO. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 6-fluoroisoquinolin-1(2H)-one is a white crystalline solid.
-Melting point: Its melting point is 132-133 ° C.
-Solubility: 6-fluoroisoquinolin-1(2H)-one is relatively soluble in common solvents.

Use:
-Chemical research: 6-fluoroisoquinolin-1(2H)-one is commonly used as an intermediate in organic synthesis and can be used to synthesize other organic compounds.
-Drug research: This compound may also have drug activity, so related drug research can be carried out.

Method:
The preparation method of 6-fluoroisoquinolin-1(2H)-one is relatively complicated and may require a series of organic synthesis steps. The preparation method usually includes the following steps:
1. First, the fluorine atom is introduced into the nucleus of isoquinoline through an appropriate chemical reaction.
2. Then, introduce a hydroxyl group on the isoquinoline structure by an appropriate method.
3. Finally, 6-fluoroisoquinolin-1(2H)-one was obtained by purification and crystallization.

Safety Information:
The toxicological properties of -6-fluoroisoquinolin-1(2H)-one are not fully understood, so appropriate safety procedures should be followed in operation.
-When handling 6-fluoroisoquinolin-1(2H)-one, use appropriate personal protective equipment, including glasses, protective gloves, and test coats.
-Exposure to food, water or the environment is not recommended due to lack of relevant toxicological data.
-If you eat or inhale by mistake, you should seek medical attention in time.

Last Update：2024-04-09 21:01:54