21409-26-7
N-Phenyl-1-(2-phenethyl)piperidin-4-amine
CAS: 21409-26-7
Molecular Formula: C19H24N2
21409-26-7 - Names and Identifiers
| Name | N-Phenyl-1-(2-phenethyl)piperidin-4-amine |
| Synonyms | Despropionylfentanyl 4-Aminophenyl-1-Phenethylpiperidine N-Phenyl-1-(2-phenethyl)piperidin-4-amine N-phenyl-1-(2-phenylethyl)piperidin-4-amine 4-Piperidinamine, N-phenyl-1-(2-phenylethyl)- |
| CAS | 21409-26-7 |
| InChI | InChI=1/C19H24N2/c1-3-7-17(8-4-1)11-14-21-15-12-19(13-16-21)20-18-9-5-2-6-10-18/h1-10,19-20H,11-16H2 |
21409-26-7 - Physico-chemical Properties
| Molecular Formula | C19H24N2 |
| Molar Mass | 280.407 |
| Density | 1.075g/cm3 |
| Melting Point | 94-96℃ |
| Boling Point | 424.6°C at 760 mmHg |
| Flash Point | 161.9°C |
| Vapor Presure | 2.04E-07mmHg at 25°C |
| Refractive Index | 1.603 |
21409-26-7 - Introduction
N-Phenyl-1-(2-phenethyl)piperidin-4-amine(N-Phenyl-1-(2-phenethyl)piperidin-4-amine) is an organic compound with the following properties:
-Molecular formula: C21H26N2
-Molecular weight: 310.448g/mol
-Appearance: White crystalline solid
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and chloroform
N-Phenyl-1-(2-phenethyl)piperidin-4-amine are often used as pharmaceutical intermediates and Organic Synthesis Reagents. It has a wide range of applications in pharmaceutical chemistry, such as the synthesis of new drug molecules, the study of drug metabolism pathways.
The method of preparing N-Phenyl-1-(2-phenethyl)piperidin-4-amine includes the following steps:
1. The reaction of 2-phenylacetaldehyde and silver nitrate to obtain the corresponding nitroalkene acetone.
2. Reaction of nitroalkene acetone with benzylamine to generate nitrobenzylamine.
3. Reduction of nitrobenzylamine to obtain N-Phenyl-1-(2-phenethyl)piperidin-4-amine.
N-Phenyl-1-(2-phenethyl)piperidin-4-amine safety information has not been fully studied and reported, so it is necessary to take appropriate protective measures when using. When used in the laboratory, you should wear protective glasses and gloves, and ensure good ventilation conditions for operation. In addition, inhalation of its dust or contact with skin and eyes should be avoided. During storage, it should be kept in a dry, cool place, away from fire and oxidizing agents.
-Molecular formula: C21H26N2
-Molecular weight: 310.448g/mol
-Appearance: White crystalline solid
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and chloroform
N-Phenyl-1-(2-phenethyl)piperidin-4-amine are often used as pharmaceutical intermediates and Organic Synthesis Reagents. It has a wide range of applications in pharmaceutical chemistry, such as the synthesis of new drug molecules, the study of drug metabolism pathways.
The method of preparing N-Phenyl-1-(2-phenethyl)piperidin-4-amine includes the following steps:
1. The reaction of 2-phenylacetaldehyde and silver nitrate to obtain the corresponding nitroalkene acetone.
2. Reaction of nitroalkene acetone with benzylamine to generate nitrobenzylamine.
3. Reduction of nitrobenzylamine to obtain N-Phenyl-1-(2-phenethyl)piperidin-4-amine.
N-Phenyl-1-(2-phenethyl)piperidin-4-amine safety information has not been fully studied and reported, so it is necessary to take appropriate protective measures when using. When used in the laboratory, you should wear protective glasses and gloves, and ensure good ventilation conditions for operation. In addition, inhalation of its dust or contact with skin and eyes should be avoided. During storage, it should be kept in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-09 20:52:54
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