2149-76-0
5-AMINOURIDINE, HYDROCHLORIDE SALT
CAS: 2149-76-0
Molecular Formula: C9H13N3O6
2149-76-0 - Names and Identifiers
2149-76-0 - Physico-chemical Properties
| Molecular Formula | C9H13N3O6 |
| Molar Mass | 259.22 |
| Density | 1.712±0.06 g/cm3(Predicted) |
| Melting Point | 214-216 °C |
| pKa | 9.31±0.10(Predicted) |
| Storage Condition | −20°C |
| In vitro study | This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy) 3 3+ . These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites. |
| In vivo study | 5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [ 32 P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma. |
2149-76-0 - Risk and Safety
| WGK Germany | 3 |
2149-76-0 - References
| biological activity | 5-Aminouridine can modify nucleobases and can be incorporated into target DNA. 5-Aminouridine exhibits a wide range of biological activity, inhibiting the growth of tumors, fungi and Virus. |
Last Update：2024-04-09 02:00:19
