215309-01-6

215309-01-6 - Names and Identifiers

Name	3-(4-Methylpiperazin-1-yl)benzoic acid
Synonyms	AKOS BB-5295 3-(4-Methylpiperazin-1-yl)Benz 3-(4-Methylpiperazin-1-yl)benzoic acid 1-(3-Carboxyphenyl)-4-methylpiperazine 3-(4-Methyl-1-piperazinyl)benzoic acid 3-(4-METHYLPIPERAZIN-1-YL)BENZOIC ACID Benzoic acid, 3-(4-methyl-1-piperazinyl)-
CAS	215309-01-6
InChI	InChI=1/C12H16N2O2/c1-13-5-7-14(8-6-13)11-4-2-3-10(9-11)12(15)16/h2-4,9H,5-8H2,1H3,(H,15,16)

215309-01-6 - Physico-chemical Properties

Molecular Formula	C12H16N2O2
Molar Mass	220.27
Density	1.188g/cm³
Melting Point	187-190 °C
Boling Point	400.2°C at 760 mmHg
Flash Point	195.8°C
Vapor Presure	4.02E-07mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.579

215309-01-6 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

215309-01-6 - Introduction

3-(4-Methylpiperazin-1-yl)benzoic acid is an organic compound with the chemical formula C13H17N3O2.

3-(4-Methylpiperazin-1-yl)benzoic acid has the following properties:
-Appearance: Colorless or slightly yellow crystalline solid.
-Solubility: Soluble in organic solvents such as ethanol and dichloromethane, slightly soluble in water.
-Melting point: About 140-142 ℃.

The main uses of this compound are as follows:
-drug intermediate: 3-(4-Methylpiperazin-1-yl)benzoic acid is a commonly used drug intermediate, which is used to synthesize some piperazine and benzoic acid compounds, such as anti-anxiety drugs, antipsychotic drugs, etc.

Regarding the preparation method, 3-(4-Methylpiperazin-1-yl)benzoic acid can be synthesized by the following steps:
1.1-(4-methyl -1-piperazine) ethanol is reacted with phthalic anhydride to obtain 1-(4-methyl -1-piperazine) benzoic acid.
2.1-(4-methyl -1-piperazine) benzoic acid is reacted with concentrated sulfuric acid to obtain 3-(4-Methylpiperazin-1-yl)benzoic acid.

Regarding safety information, the specific toxicological properties and safety guidelines for 3-(4-Methylpiperazin-1-yl)benzoic acid may vary by country and region, it is recommended to follow the relevant safety operating procedures during use and refer to the relevant safety data sheets. As a chemical, it should be kept away from open flames and heat sources, and stored in a dry, well-ventilated place.

Last Update：2024-04-09 21:49:45