215599-91-0
1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride
CAS: 215599-91-0
Molecular Formula: C7H9ClFNO
215599-91-0 - Names and Identifiers
215599-91-0 - Physico-chemical Properties
| Molecular Formula | C7H9ClFNO |
| Molar Mass | 177.6 |
| Melting Point | 180-185°C |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD01114584 |
215599-91-0 - Risk and Safety
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Class | IRRITANT |
215599-91-0 - Introduction
1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is an organic compound with the chemical formula C7H8FNO · HCl. Its properties are as follows:
1. Appearance: white crystalline solid
2. melting point: about 115-118 degrees Celsius
3. Solubility: Soluble in water and some organic solvents, such as methanol and dimethyl ether
1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is mainly used in condensation reactions in organic synthesis, such as reactions with aldehydes and ketones, which can generate hydroxoximes. These hydroxoximes have important applications in drug synthesis and the construction of heterocyclic compounds.
The method of preparing 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is generally achieved by reduction of nitrate. First, 2-fluorobenzene is reacted to form 2-fluorobenzylhydroxylamine, which is then reacted with hydrochloric acid to form 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride.
Regarding safety information, 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is a relatively stable compound under general conditions, but the following matters still need to be noted:
1. Avoid direct contact with skin and eyes to avoid irritation and damage.
2. use to wear appropriate personal protective equipment, such as gloves and goggles.
3. Storage should avoid high temperature, humidity and open flame, keep the container sealed.
Although there are no public reports of acute or chronic toxicity of 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride, it is recommended to follow laboratory safety practices and follow proper storage and disposal practices. If necessary, refer to the relevant Safety Data Sheet (SDS) or consult the chemical supplier for more detailed safety information.
1. Appearance: white crystalline solid
2. melting point: about 115-118 degrees Celsius
3. Solubility: Soluble in water and some organic solvents, such as methanol and dimethyl ether
1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is mainly used in condensation reactions in organic synthesis, such as reactions with aldehydes and ketones, which can generate hydroxoximes. These hydroxoximes have important applications in drug synthesis and the construction of heterocyclic compounds.
The method of preparing 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is generally achieved by reduction of nitrate. First, 2-fluorobenzene is reacted to form 2-fluorobenzylhydroxylamine, which is then reacted with hydrochloric acid to form 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride.
Regarding safety information, 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride is a relatively stable compound under general conditions, but the following matters still need to be noted:
1. Avoid direct contact with skin and eyes to avoid irritation and damage.
2. use to wear appropriate personal protective equipment, such as gloves and goggles.
3. Storage should avoid high temperature, humidity and open flame, keep the container sealed.
Although there are no public reports of acute or chronic toxicity of 1-[(Aminooxy)methyl]-2-fluorobenzene hydrochloride, it is recommended to follow laboratory safety practices and follow proper storage and disposal practices. If necessary, refer to the relevant Safety Data Sheet (SDS) or consult the chemical supplier for more detailed safety information.
Last Update：2024-04-09 21:01:54
