2181-98-8

2181-98-8 - Names and Identifiers

Name	Methyl 4-(triphenylphosphonio)crotonate bromide
Synonyms	METHYL-4-(TRIPHENYLPHOSPONIO)CROTONATE BROMIDE Methyl 4-(triphenylphosphonio)crotonate bromide METHYL 4-(TRIPHENYLPHOSPHONIO)CROTONATE BROMIDE (4-methoxy-4-oxo-2-butenyl)triphenylphosphonium bromide (4-Methoxy-4-oxobut-2-en-1-yl)triphenylphosphonium bromide (3-Methoxycarbonyl-2-propenyl)triphenylphosphonium bromide (E)-4-methoxy-4-oxo-but-2-enyl]-triphenyl-phosphonium bromide [(2E)-4-methoxy-4-oxobut-2-en-1-yl](triphenyl)phosphonium bromide
CAS	2181-98-8
EINECS	218-557-5
InChI	InChI=1/C23H22O2P.BrH/c1-25-23(24)18-11-19-26(20-12-5-2-6-13-20,21-14-7-3-8-15-21)22-16-9-4-10-17-22;/h2-18H,19H2,1H3;1H/q+1;/p-1/b18-11+

2181-98-8 - Physico-chemical Properties

Molecular Formula	C23H22BrO2P
Molar Mass	441.3
Melting Point	175°C (dec.)
BRN	4173385
Storage Condition	Room Temprature
Sensitive	Hygroscopic
MDL	MFCD00031575

2181-98-8 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.

2181-98-8 - Introduction

Methyl 4-(triphenylphosphonium) crotonate bromide (Methyl 4-(triphenylphosphonio)crotonate bromide) is an organic compound with the chemical formula C25H21BrO2P.

The properties of the compound are as follows:
-Appearance: White or light yellow crystal or crystalline powder
-Solubility: Soluble in organic solvents, such as alcohol, ether, etc
-Thermal stability: decomposition at high temperature

Methyl 4-(triphenylphosphonio)crotonate bromide is commonly used as a reagent in organic synthetic chemistry. Specific uses include:
-Catalyst: It can be used as a catalyst for organic synthesis reactions, such as boron alcohol esterification of olefins and Michael addition reactions.
-Inducer: It can induce certain chemical reactions, such as the reaction of thiols and aldehydes in the aqueous phase.
-Reagent: Used as a reagent in some chemical analysis methods.

The method of preparing Methyl 4-(triphenylphosphonio)crotonate bromide is generally through the following steps:
1. The crotonate methyl ester (methyl crotonate) and triphenyl phosphine (triphenyl phosphine) are mixed and reacted to generate crotonate methyl ester phosphonium salt (crotonate phosphonium salt).
2. Add hydrogen bromide (HBr) into the reaction system to make the reaction of phosphonium salt of Methyl crotonate and HBr, and form the final product Methyl 4-(triphenylphosphonio)crotonate bromide.
3. The product was crystallized and purified to give the desired compound.

For safety information on this compound, note the following:
-The substance may be irritating, and necessary safety measures should be taken when exposed, such as wearing gloves, goggles, etc.
-Avoid inhaling the gas, dust or smoke of the compound.
-Should be stored in a dry, cool place and avoid contact with oxidizing agents.

Last Update：2024-04-10 22:29:15