220227-84-9

220227-84-9 - Names and Identifiers

Name	3-(trifluoromethoxy)benzene-1-sulfonyl chloride
Synonyms	3-(TRIFLUOROMETHOXY)BENZENESULFONYL CHLORIDE 3-(Trifluoromethoxy)benzenesulfonyl chloride 3-(TRIFLUOROMETHOXY)BENZENESULPHONYL CHLORIDE 3-(TRIFLUOROMETHOXY)BENZENE-1-SULFONYL CHLORIDE 3-(trifluoromethoxy)benzene-1-sulfonyl chloride 3-(Chlorosulphonyl)-alpha, alpha,alpha-trifluoroanisole
CAS	220227-84-9
EINECS	624-326-3
InChI	InChI=1/C7H4ClF3O3S/c8-15(12,13)6-3-1-2-5(4-6)14-7(9,10)11/h1-4H

220227-84-9 - Physico-chemical Properties

Molecular Formula	C7H4ClF3O3S
Molar Mass	260.62
Density	1.530g/mLat 25°C(lit.)
Melting Point	229-230℃
Boling Point	229-230°C(lit.)
Flash Point	>230°F
Vapor Presure	0.0187mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Light yellow to Light orange
Storage Condition	2-8°C
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.4760(lit.)

220227-84-9 - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection. S37 - Wear suitable gloves. S36 - Wear suitable protective clothing.
UN IDs	UN 3265 8/PG 2
WGK Germany	3
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

220227-84-9 - Introduction

3-(trifluoromethoxy)benzene-1-sulfonyl chloride is an organic compound with the chemical formula C7H4ClF3O2S and a molecular weight of 252.62g/mol.

Nature:
-Appearance: colorless or yellowish liquid
-Melting point: 29-31 ℃
-Boiling point: 103-105 ℃
-Density: 1.68g/cm3
-Soluble: Soluble in ethanol and chloroform

Use:
3-(trifluoromethoxy)benzene-1-sulfonyl chloride has important application value in chemical synthesis and is often used as a reagent in organic synthesis. It can be used in organic synthesis in the fluorination reaction, condensation reaction, dehydration reaction and aromatization reaction. The compound also has certain applications in the fields of medicine, pesticide, photoelectric materials and so on.

Method:
3-(trifluoromethoxy)benzene-1-sulfonyl chloride can be obtained by reacting benzene tricarboxylic acid with trifluoromethyl alcohol. First, an excess amount of trifluoromethyl alcohol was added to the reaction system, and then trimellitic acid was added, and the reaction temperature and time were controlled. Finally, the target product is purified by distillation.

Safety Information:
3-(trifluoromethoxy)benzene-1-sulfonyl chloride is an organic substance and should be handled with care. It may be irritating to the eyes, skin and respiratory tract, so contact should be avoided. Appropriate protective equipment such as safety glasses, gloves and face shields should be used during use. Keep away from fire and avoid contact with flammable materials during storage and handling. In case of accidental ingestion or contact, seek medical attention immediately. Consult the relevant safety data sheets and operating instructions when handling this compound.

Last Update：2024-04-09 21:01:54