220607-75-0
2-bromo-1-(3,5-difluorophenyl)ethanone
CAS: 220607-75-0
Molecular Formula: C8H5BrF2O
220607-75-0 - Names and Identifiers
| Name | 2-bromo-1-(3,5-difluorophenyl)ethanone |
| Synonyms | 3,5-DIFLUOROPHENACYL BROMIDE 3',5'-DIFLUOROPHENACYL BROMIDE 2-BROMO-3,5-DIFLUOROACETOPHENONE 2-Bromo-3',5'-difluoroacetophenone 2-bromo-1-(3,5-difluorophenyl)ethanone 2-Bromo-1-(3,5-difluorophenyl)ethanone 2-bromo-1-(3,5-difluorophenyl)ethan-1-one Ethanone, 2-bromo-1-(3,5-difluorophenyl)- 2-Bromo-3',5'-difluoroacetophenone, 2-Bromo-1-(3,5-difluorophenyl)ethan-1-one |
| CAS | 220607-75-0 |
| InChI | InChI=1/C8H5BrF2O/c9-4-8(12)5-1-6(10)3-7(11)2-5/h1-3H,4H2 |
220607-75-0 - Physico-chemical Properties
| Molecular Formula | C8H5BrF2O |
| Molar Mass | 235.03 |
| Density | 1.648g/cm3 |
| Boling Point | 246℃ |
| Flash Point | 102℃ |
| Vapor Presure | 0.0281mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.529 |
220607-75-0 - Risk and Safety
| Hazard Note | Flammable/Corrosive |
220607-75-0 - Introduction
2-bromo-1-(3,5-difluorophenyl)ethanone is an organic compound with the chemical formula C8H6BrF2O. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow solid
-Molecular weight: 227.04g/mol
-Boiling Point: 267-268 ° C
-Melting point: 39-40 ° C
-Density: 1.67g/cm³ (25 ° C)
-Solubility: Soluble in organic solvents such as ethanol, acetone and dichloromethane
Use:
- 2-bromo-1-(3,5-difluorophenyl)ethanone can be used as an important intermediate in organic synthesis.
-It can be used to synthesize compounds containing aromatic rings and carbonyl functional groups, such as drugs, dyes and pesticides.
Method:
The preparation of 2-bromo-1-(3,5-difluorophenyl)ethanone can be carried out by the following steps:
1.3,5-difluoroacetophenone reacts with bromine in ether to generate the corresponding brominated reactant.
2. Purify by crystallization or column chromatography to obtain the target product.
Safety Information:
- 2-bromo-1-(3,5-difluorophenyl)ethanone is irritating, so safe operating procedures should be followed during operation.
-Avoid contact with skin, eyes and mucous membranes. If touched by mistake, rinse immediately with plenty of water and seek medical help.
-During use, ensure good ventilation and avoid inhaling the gas or vapor of the compound.
-When storing, it should be placed in a sealed container, away from high temperature and fire sources.
-Do not mix it with substances such as strong oxidants, strong acids or strong bases.
Nature:
-Appearance: Colorless to light yellow solid
-Molecular weight: 227.04g/mol
-Boiling Point: 267-268 ° C
-Melting point: 39-40 ° C
-Density: 1.67g/cm³ (25 ° C)
-Solubility: Soluble in organic solvents such as ethanol, acetone and dichloromethane
Use:
- 2-bromo-1-(3,5-difluorophenyl)ethanone can be used as an important intermediate in organic synthesis.
-It can be used to synthesize compounds containing aromatic rings and carbonyl functional groups, such as drugs, dyes and pesticides.
Method:
The preparation of 2-bromo-1-(3,5-difluorophenyl)ethanone can be carried out by the following steps:
1.3,5-difluoroacetophenone reacts with bromine in ether to generate the corresponding brominated reactant.
2. Purify by crystallization or column chromatography to obtain the target product.
Safety Information:
- 2-bromo-1-(3,5-difluorophenyl)ethanone is irritating, so safe operating procedures should be followed during operation.
-Avoid contact with skin, eyes and mucous membranes. If touched by mistake, rinse immediately with plenty of water and seek medical help.
-During use, ensure good ventilation and avoid inhaling the gas or vapor of the compound.
-When storing, it should be placed in a sealed container, away from high temperature and fire sources.
-Do not mix it with substances such as strong oxidants, strong acids or strong bases.
Last Update：2024-04-09 20:49:11
