220705-28-2
3-(1,3-Benzoxazol-2-yl)-4-fluoroaniline
CAS: 220705-28-2
Molecular Formula: C13H9FN2O
220705-28-2 - Names and Identifiers
220705-28-2 - Physico-chemical Properties
| Molecular Formula | C13H9FN2O |
| Molar Mass | 228.22 |
| Melting Point | 153-156 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD03425815 |
220705-28-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
220705-28-2 - Introduction
3-(1,3-benzoxazol-2-yl)-4-fluoroaniline is an organic compound with the chemical formula C13H9FN2O. It is a white crystalline solid with an oily appearance. 3-(1,3-benzoxazol-2-yl)-4-fluoroaniline contains a benzene ring, a benzoxazole ring, and a fluorine atom in the chemical structure.
This compound has certain application value in drug synthesis and material science. It can be used as a raw material for fluorescent dyes, which can emit grass green fluorescence in fluorescence analysis and biological imaging. In addition, it can also be used as a drug intermediate, with potential anti-tumor and anti-cancer activities.
The method for preparing 3-(1,3-benzoxazol-2-yl)-4-fluoroaniline includes the following steps: First, 2-aminophenol and hydroquinone are reacted under appropriate conditions to generate 1,3-benzoxazolone; Then, the ketone is reacted with 4-fluorobenzene borate to synthesize the final target product through ring formation.
As for safety information, 3-(1,3-benzoxazol-2-yl)-4-fluoroaniline should be aware of its toxicity. During handling and storage, it is necessary to take appropriate protective measures to prevent contact with the skin and inhalation of aerosols. Wear appropriate personal protective equipment such as goggles and gloves during use or handling.
The compound should be kept away from fire and oxidizing agents, and stored in a cool and dry place. In the process of use, please closely follow the chemical safety regulations and avoid mixing with other chemical substances. In the event of a spill or accident, immediate removal measures should be taken to ensure the safety of the environment and individuals. If necessary, consult a professional for more detailed safety information.
This compound has certain application value in drug synthesis and material science. It can be used as a raw material for fluorescent dyes, which can emit grass green fluorescence in fluorescence analysis and biological imaging. In addition, it can also be used as a drug intermediate, with potential anti-tumor and anti-cancer activities.
The method for preparing 3-(1,3-benzoxazol-2-yl)-4-fluoroaniline includes the following steps: First, 2-aminophenol and hydroquinone are reacted under appropriate conditions to generate 1,3-benzoxazolone; Then, the ketone is reacted with 4-fluorobenzene borate to synthesize the final target product through ring formation.
As for safety information, 3-(1,3-benzoxazol-2-yl)-4-fluoroaniline should be aware of its toxicity. During handling and storage, it is necessary to take appropriate protective measures to prevent contact with the skin and inhalation of aerosols. Wear appropriate personal protective equipment such as goggles and gloves during use or handling.
The compound should be kept away from fire and oxidizing agents, and stored in a cool and dry place. In the process of use, please closely follow the chemical safety regulations and avoid mixing with other chemical substances. In the event of a spill or accident, immediate removal measures should be taken to ensure the safety of the environment and individuals. If necessary, consult a professional for more detailed safety information.
Last Update：2024-04-09 22:09:11
